The accuracy of healthcare worker versus self collected (2-in-1) Oropharyngeal and Bilateral Mid-Turbinate (OPMT) swabs and saliva samples for SARS-CoV-2

by Tan, Seow Yen, Tey, Hong Liang, Lim, Ernest Tian Hong, Toh, Song Tar, Chan, Yiong Huak, Tan, Pei Ting, Lee, Sing Ai, Tan, Cheryl Xiaotong, Koh, Gerald Choon Huat, Tan, Thean Yen, Siau, Chuin
Published 2022

Differential cytokine responses in hospitalized COVID-19 patients limit efficacy of Remdesivir

by Chan, Yi-Hao, Young, Barnaby Edward, Fong, Siew-Wai, Ding, Ying, Goh, Yun Shan, Chee, Rhonda Sin-Ling, Tan, Seow-Yen, Kalimuddin, Shirin, Tambyah, Paul A., Leo, Yee Sin, Ng, Lisa F. P., Lye, David C., Renia, Laurent
Published 2022

Early oral stepdown antibiotic therapy versus continuing intravenous therapy for uncomplicated Gram-negative bacteraemia (the INVEST trial): Study protocol for a multicentre, rando...

by Lee, I. Russel, Tong, Steven Y. C., Davis, Joshua S., Paterson, David L., Syed Omar, Sharifah Faridah, Peck, Kwong Ran, Chung, Doo Ryeon, Cooke, Graham S., Libau, Eshele Anak, Rahman, Siti-Nabilah B. A., Gandhi, Mihir P., Shi, Luming, Zheng, Shuwei, Chaung, Jenna, Tan, Seow Yen, Kalimuddin, Shirin, Archuleta, Sophia, Lye, David C.
Published 2022

Persistent symptoms and association with inflammatory cytokine signatures in recovered coronavirus disease 2019 patients

by Ong, Sean Wei Xiang, Fong, Siew-Wai, Young, Barnaby Edward, Chan, Yi-Hao, Lee, Bernett, Siti Naqiah Amrun, Chee, Rhonda Sin-Ling, Yeo, Nicholas Kim-Wah, Tambyah, Paul, Pada, Surinder, Tan, Seow Yen, Ding, Ying, Renia, Laurent, Leo, Yee Sin, Ng, Lisa F. P., Lye, David C.
Published 2022

Persistent Symptoms and Association With Inflammatory Cytokine Signatures in Recovered Coronavirus Disease 2019 Patients.

by Ong, Sean Wei Xiang, Fong, Siew-Wai, Young, Barnaby Edward, Chan, Yi-Hao, Lee, Bernett, Amrun, Siti Naqiah, Chee, Rhonda Sin-Ling, Yeo, Nicholas Kim-Wah, Tambyah, Paul, Pada, Surinder, Tan, Seow Yen, Ding, Ying, Renia, Laurent, Leo, Yee-Sin, Ng, Lisa FP, Lye, David Chien
Published 2021

Early oral stepdown antibiotic therapy versus continuing intravenous therapy for uncomplicated Gram-negative bacteraemia (the INVEST trial): study protocol for a multicentre, rando...

by Lee, I Russel, Tong, Steven YC, Davis, Joshua S, Paterson, David L, Syed-Omar, Sharifah F, Peck, Kwong Ran, Chung, Doo Ryeon, Cooke, Graham S, Libau, Eshele Anak, Rahman, Siti-Nabilah BA, Gandhi, Mihir P, Shi, Luming, Zheng, Shuwei, Chaung, Jenna, Tan, Seow Yen, Kalimuddin, Shirin, Archuleta, Sophia, Lye, David C
Published 2022

Convalescent COVID-19 patients are susceptible to endothelial dysfunction due to persistent immune activation

by Chioh, Florence WJ, Fong, Siew-Wai, Young, Barnaby E, Wu, Kan-Xing, Siau, Anthony, Krishnan, Shuba, Chan, Yi-Hao, Carissimo, Guillaume, Teo, Louis LY, Gao, Fei, Tan, Ru San, Zhong, Liang, Koh, Angela S, Tan, Seow-Yen, Tambyah, Paul A, Renia, Laurent, Ng, Lisa FP, Lye, David C, Cheung, Christine
Published 2022

Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections

by Goh, Yun Shan, Fong, Siew-Wai, Hor, Pei Xiang, Siti Naqiah Amrun, Lee, Cheryl Yi-Pin, Young, Barnaby Edward, Chia, Po Ying, Tambyah, Paul A., Kalimuddin, Shirin, Pada, Surinder, Tan, Seow-Yen, Sun, Louisa Jin, Chen, Mark I-Cheng, Leo, Yee-Sin, Lye, David C., Ng, Lisa F. P., Renia, Laurent
Published 2023

Convalescent COVID-19 patients are susceptible to endothelial dysfunction due to persistent immune activation

by Chioh, Florence Wen Jing, Fong, Siew-Wai, Young, Barnaby Edward, Wu, Kan Xing, Siau, Anthony, Krishnan, Shuba, Chan, Yi-Hao, Carissimo, Guillaume, Teo, Louis L. Y., Gao, Fei, Tan, Ru San, Zhong, Liang, Koh, Angela S., Tan, Seow-Yen, Tambyah, Paul A., Renia, Laurent, Ng, Lisa F. P., Lye, David C., Cheung, Christine
Published 2021

Resistance of SARS-CoV-2 variants to neutralization by convalescent plasma from early COVID-19 outbreak in Singapore

by Wang, Bei, Goh, Yun Shan, Prince, Tessa, Ngoh, Eve Zi Xian, Salleh, Siti Nazihah Mohd, Hor, Pei Xiang, Loh, Chiew Yee, Fong, Siew Wai, Hartley, Catherine, Tan, Seow-Yen, Young, Barnaby Edward, Leo, Yee-Sin, Lye, David C., Maurer-Stroh, Sebastian, Ng, Lisa F. P., Hiscox, Julian A., Renia, Laurent, Wang, Cheng-, I
Published 2022

Resistance of SARS-CoV-2 variants to neutralization by convalescent plasma from early COVID-19 outbreak in Singapore

by Wang, Bei, Goh, Yun Shan, Prince, Tessa, Ngoh, Eve Zi Xian, Salleh, Siti Nazihah Mohd, Hor, Pei Xiang, Loh, Chiew Yee, Fong, Siew Wai, Hartley, Catherine, Tan, Seow-Yen, Young, Barnaby Edward, Leo, Yee Sin, Lye, David Chien Boon, Maurer-Stroh, Sebastian, Ng, Lisa F. P., Hiscox, Julian A., Renia, Laurent, Wang, Cheng-I
Published 2021

Prolonged inflammation in patients hospitalized for coronavirus disease 2019 (COVID-19) resolves 2 years after infection

by Fong, Siew-Wai, Goh, Yun Shan, Torres-Ruesta, Anthony, Chang, Zi Wei, Chan, Yi-Hao, Neo, Vanessa Kexin, Lee, Bernett, Duan, Kaibo, Amrun, Siti Naqiah, Yeo, Nicholas Kim-Wah, Chen, Hsiuyi V., Tay, Matthew Zirui, Carissimo, Guillaume, Tan, Seow Yen, Leo, Yee Sin, Lye, David C., Renia, Laurent, Young, Barnaby Edward, Ng, Lisa F. P.
Published 2023

Virological and serological kinetics of SARS-CoV-2 Delta variant vaccine breakthrough infections: a multicentre cohort study

by Chia, Po Ying, Ong, Sean Wei Xiang, Chiew, Calvin J., Ang, Li Wei, Chavatte, Jean-Marc, Mak, Tze-Minn, Cui, Lin, Kalimuddin, Shirin, Chia, Wan Ni, Tan, Chee Wah, Chai, Louis Yi Ann, Tan, Seow Yen, Zheng, Shuwei, Lin, Raymond Tzer Pin, Wang, Linfa, Leo, Yee Sin, Lee, Vernon J., Lye, David C., Young, Barnaby Edward
Published 2022

Longitudinal single cell atlas identifies complex temporal relationship between type I interferon response and COVID-19 severity

by Lin, Quy Xiao Xuan, Rajagopalan, Deepa, Gamage, Akshamal M., Tan, Le Min, Venkatesh, Prasanna Nori, Chan, Wharton O. Y., Kumar, Dilip, Agrawal, Ragini, Chen, Yao, Fong, Siew-Wai, Singh, Amit, Sun, Louisa J., Tan, Seow-Yen, Chai, Louis Yi Ann, Somani, Jyoti, Lee, Bernett, Renia, Laurent, Ng, Lisa F. P., Ramanathan, Kollengode, Wang, Lin-Fa, Young, Barnaby, Lye, David, Singhal, Amit, Prabhakar, Shyam
Published 2024

Clinical features and predictors of severity in COVID-19 patients with critical illness in Singapore

by Puah, Ser Hon, Young, Barnaby Edward, Chia, Po Ying, Ho, Vui Kian, Loh, Jiashen, Gokhale, Roshni Sadashiv, Tan, Seow Yen, Sewa, Duu Wen, Kalimuddin, Shirin, Tan, Chee Keat, Pada, Surinder KMS, Cove, Matthew Edward, Chai, Louis Yi Ann, Parthasarathy, Purnima, Ho, Benjamin Choon Heng, Ng, Jensen Jiansheng, Ling, Li Min, Abisheganaden, John A, Lee, Vernon JM, Tan, Cher Heng, Lin, Raymond TP, Leo, Yee Sin, Lye, David C, Yeo, Tsin Wen
Published 2021

Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity

by Siti Naqiah Amrun, Lee, Cheryl Yi-Pin, Lee, Bernett, Fong, Siew-Wai, Young, Barnaby Edward, Chee, Rhonda Sin-Ling, Yeo, Nicholas Kim-Wah, Torres-Ruesta, Anthony, Carissimo, Guillaume, Poh, Chek Meng, Chang, Zi Wei, Tay, Matthew Zirui, Chan, Yi-Hao, Chen, Mark I-Cheng, Low, Jenny Guek-Hong, Tambyah, Paul A., Kalimuddin, Shirin, Pada, Surinder, Tan, Seow-Yen, Sun, Louisa Jin, Leo, Yee-Sin, Lye, David C., Renia, Laurent, Ng, Lisa F. P.
Published 2020

Association of SARS-CoV-2 clades with clinical, inflammatory and virologic outcomes: an observational study

by Young, Barnaby Edward, Wei, Wycliffe E., Fong, Siew-Wai, Mak, Tze-Minn, Anderson, Danielle E., Chan, Yi-Hao, Pung, Rachael, Heng, Cheryl S. Y., Ang, Li Wei, Zheng, Adrian Kang Eng, Lee, Bernett, Kalimuddin, Shirin, Pada, Surinder, Tambyah, Paul A., Parthasarathy, Purnima, Tan, Seow Yen, Sun, Louisa, Smith, Gavin J. D., Lin, Raymond Tzer Pin, Leo, Yee Sin, Renia, Laurent, Wang, Lin-Fa, Ng, Lisa F. P., Maurer-Stroh, Sebastian, Lye, David C., Lee, Vernon J.
Published 2022

Asymptomatic COVID-19: disease tolerance with efficient anti-viral immunity against SARS-CoV-2

by Chan, Yi-Hao, Fong, Siew-Wai, Poh, Chek-Meng, Carissimo, Guillaume, Yeo, Nicholas Kim-Wah, Amrun, Siti Naqiah, Goh, Yun Shan, Lim, Jackwee, Xu, Weili, Chee, Rhonda Sin-Ling, Torres-Ruesta, Anthony, Lee, Cheryl Yi-Pin, Tay, Matthew Zirui, Chang, Zi Wei, Lee, Wen-Hsin, Wang, Bei, Tan, Seow-Yen, Kalimuddin, Shirin, Young, Barnaby Edward, Leo, Yee-Sin, Wang, Cheng-, I, Lee, Bernett, Rötzschke, Olaf, Lye, David Chien, Renia, Laurent, Ng, Lisa F. P.
Published 2022

Clinical features and predictors of severity in COVID-19 patients with critical illness in Singapore.

by Ser Hon Puah, Puah, Ser Hon, Young, Barnaby Edward, Chia, Po Ying, Ho, Vui Kian, Loh, Jiashen, Gokhale, Roshni Sadashiv, Tan, Seow Yen, Sewa, Duu Wen, Kalimuddin, Shirin, Tan, Chee Keat, Pada, Surinder KMS, Cove, Matthew Edward, Chai, Louis Yi Ann, Parthasarathy, Purnima, Ho, Benjamin Choon Heng, Ng, Jensen Jiansheng, Ling, Li Min, Abisheganaden, John A, Lee, Vernon JM, Tan, Cher Heng, Lin, Raymond TP, Leo, Yee Sin, Lye, David C, Yeo, Tsin Wen
Published 2021

Association of SARS-CoV-2 clades with clinical, inflammatory and virologic outcomes: An observational study

by Young, Barnaby E, Wei, Wycliffe E, Fong, Siew-Wai, Mak, Tze-Minn, Anderson, Danielle E, Chan, Yi-Hao, Pung, Rachael, Heng, Cheryl SY, Ang, Li Wei, Zheng, Adrian Kang Eng, Lee, Bernett, Kalimuddin, Shirin, Pada, Surinder, Tambyah, Paul A, Parthasarathy, Purnima, Tan, Seow Yen, Sun, Louisa, Smith, Gavin JD, Lin, Raymond Tzer Pin, Leo, Yee-Sin, Renia, Laurent, Wang, Lin-Fa, Ng, Lisa FP, Maurer-Stroh, Sebastian, Lye, David Chien, Lee, Vernon J
Published 2021