Stool metagenome analysis of patients with Klebsiella pneumoniae liver abscess and their domestic partners

by Molton, James S., Lee, I. Russel, Bertrand, Denis, Ding, Ying, Kalimuddin, Shirin, Lye, David C., Nagarajan, Niranjan, Gan, Yunn-Hwen, Archuleta, Sophia
Published 2021

Stool metagenome analysis of patients with Klebsiella pneumoniae liver abscess and their domestic partners

by Molton, James S., Lee, I. Russel, Bertrand, Denis, Ding, Ying, Kalimuddin, Shirin, Lye, David C., Nagarajan, Niranjan, Gan, Yunn-Hwen, Archuleta, Sophia
Published 2022

An experimental medicine decipher of a minimum correlate of cellular immunity: Study protocol for a double-blind randomized controlled trial

by Kalimuddin, Shirin, Chan, Yvonne FZ, Sessions, October M, Chan, Kuan Rong, Ong, Eugenia Z, Low, Jenny G, Bertoletti, Antonio, Ooi, Eng Eong
Published 2023

Acquisition of regulator on virulence plasmid of hypervirulent Klebsiella allows bacterial lifestyle switch in response to iron

by Chu, Wilson HW, Tan, Yi Han, Tan, Si Yin, Chen, Yahua, Yong, Melvin, Lye, David C, Kalimuddin, Shirin, Archuleta, Sophia, Gan, Yunn-Hwen
Published 2023

Comparison of diabetic and non-diabetic human leukocytic responses to different capsule types of klebsiella pneumoniae responsible for causing pyogenic liver abscess

by Lee, I. Russel, Sng, Ethel, Lee, Kok-Onn, Molton, James S., Chan, Monica, Kalimuddin, Shirin, Izharuddin, Ezlyn, Lye, David C., Archuleta, Sophia, Gan, Yunn-Hwen
Published 2018

Cefazolin versus ceftriaxone as definitive treatment for Klebsiella pneumoniae bacteraemia: a retrospective multicentre study in Singapore

by Lee, I Russel, Tun-Linn, Thein, Ang, Li Wei, Ding, Ying, Lim, Jonathan J, Bok, Chwee Fang, Mukherjee, Shilpa, Titin, Christina, Kalimuddin, Shirin, Archuleta, Sophia, Lye, David C
Published 2022

Temporal dynamics of the host molecular responses underlying severe COVID-19 progression and disease resolution

by Ong, Eugenia Z., Kalimuddin, Shirin, Chia, Wen Chong, Ooi, Sarah H., Koh, Clara Wt, Tan, Hwee Cheng, Zhang, Summer L., Low, Jenny G., Ooi, Eng Eong, Chan, Kuan Rong
Published 2022

Early peripheral blood MCEMP1 and HLA-DRA expression predicts COVID-19 prognosis

by Chan, Kuan Rong, Koh, Clara WT, Ng, Dorothy HL, Qin, Shijie, Ooi, Justin SG, Ong, Eugenia Z, Zhang, Summer LX, Sam, Huizhen, Kalimuddin, Shirin, Low, Jenny GH, Ooi, Eng Eong
Published 2023

18F-fluorodeoxyglucose positron emission tomography as a window into human dengue pathophysiology

by Kalimuddin, Shirin, Xie, Wanying, Watanabe, Satoru, Tham, Jing Yang, Sam, Huizhen, Chan, Kitti Wing Ki, Yap, Tiang Siew, Totman, John J., Chacko, Ann-Marie, Vasudevan, Subhash G., Low, Jenny G.
Published 2022

Validation of self-collected buccal swab and saliva as a diagnostic tool for COVID-19

by Ku, Chee Wai, Shivani, Durai, Kwan, Jacqueline Q. T., Loy, See Ling, Erwin, Christina, Ko, Karrie K. K., Ng, Xiang Wen, Oon, Lynette, Thoon, Koh Cheng, Kalimuddin, Shirin, Chan, Jerry K. Y.
Published 2022

The higher prevalence of extended spectrum beta-lactamases among Escherichia coli ST131 in Southeast Asia is driven by expansion of a single, locally prevalent subclone

by Chen, Swaine Lin, Ding, Ying, Apisarnthanarak, Anucha, Kalimuddin, Shirin, Archuleta, Sophia, Sharifah Faridah Syed Omar, De, Partha Pratim, Koh, Tse Hsien, Chew, Kean Lee, Nadia Atiya, Suwantarat, Nuntra, Velayuthan, Rukumani Devi, Wong, Joshua Guo Xian, Lye, David C.
Published 2020

Differential cytokine responses in hospitalized COVID-19 patients limit efficacy of Remdesivir

by Chan, Yi-Hao, Young, Barnaby Edward, Fong, Siew-Wai, Ding, Ying, Goh, Yun Shan, Chee, Rhonda Sin-Ling, Tan, Seow-Yen, Kalimuddin, Shirin, Tambyah, Paul A., Leo, Yee Sin, Ng, Lisa F. P., Lye, David C., Renia, Laurent
Published 2022

The higher prevalence of extended spectrum beta-lactamases among Escherichia coli ST131 in Southeast Asia is driven by expansion of a single, locally prevalent subclone

by Chen, Swaine L, Ding, Ying, Apisarnthanarak, Anucha, Kalimuddin, Shirin, Archuleta, Sophia, Omar, Sharifah Faridah Syed, De, Partha Pratim, Koh, Tse Hsien, Chew, Kean Lee, Atiya, Nadia, Suwantarat, Nuntra, Velayuthan, Rukumani Devi, Wong, Joshua Guo Xian, Lye, David C
Published 2021

The higher prevalence of extended spectrum beta-lactamases among Escherichia coli ST131 in Southeast Asia is driven by expansion of a single, locally prevalent subclone (vol 9, 132...

by Chen, Swaine L, Ding, Ying, Apisarnthanarak, Anucha, Kalimuddin, Shirin, Archuleta, Sophia, Omar, Sharifah Faridah Syed, De, Partha Pratim, Koh, Tse Hsien, Chew, Kean Lee, Atiya, Nadia, Suwantarat, Nuntra, Velayuthan, Rukumani Devi, Wong, Joshua Guo Xian, Lye, David C
Published 2021

Early oral stepdown antibiotic therapy versus continuing intravenous therapy for uncomplicated Gram-negative bacteraemia (the INVEST trial): Study protocol for a multicentre, rando...

by Lee, I. Russel, Tong, Steven Y. C., Davis, Joshua S., Paterson, David L., Syed Omar, Sharifah Faridah, Peck, Kwong Ran, Chung, Doo Ryeon, Cooke, Graham S., Libau, Eshele Anak, Rahman, Siti-Nabilah B. A., Gandhi, Mihir P., Shi, Luming, Zheng, Shuwei, Chaung, Jenna, Tan, Seow Yen, Kalimuddin, Shirin, Archuleta, Sophia, Lye, David C.
Published 2022

Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients

by Tan, Anthony T., Linster, Martin, Tan, Chee Wah, Le Bert, Nina, Chia, Wan Ni, Kunasegaran, Kamini, Zhuang, Yan, Tham, Christine Y. L., Chia, Adeline, Smith, Gavin J. D., Young, Barnaby, Kalimuddin, Shirin, Low, Jenny G. H., Lye, David, Wang, Lin-Fa, Bertoletti, Antonio
Published 2022

Meropenem versus piperacillin-tazobactam for definitive treatment of bloodstream infections caused by AmpC β-lactamase-producing Enterobacter spp, Citrobacter freundii, Morganella...

by Stewart, Adam G., Paterson, David L., Young, Barnaby, Lye, David C., Davis, Joshua S., Schneider, Kellie, Yilmaz, Mesut, Dinleyici, Rumeysa, Runnegar, Naomi, Henderson, Andrew, Archuleta, Sophia, Kalimuddin, Shirin, Forde, Brian M., Chatfield, Mark D., Bauer, Michelle J., Lipman, Jeffrey, Harris-Brown, Tiffany, Harris, Patrick N. A.
Published 2021

Gut Ruminococcaceae levels at baseline correlate with risk of antibiotic-associated diarrhea

by Gu, Xiaoqiong, Sim, Jean X. Y., Lee, Wei Lin, Cui, Liang, Chan, Yvonne F. Z., Chang, Ega Danu, Teh, Yii Ean, Zhang, An-Ni, Armas, Federica, Chandra, Franciscus, Chen, Hongjie, Zhao, Shijie, Lee, Zhanyi, Thompson, Janelle, Ooi, Eng Eong, Low, Jenny G., Alm, Eric J., Kalimuddin, Shirin
Published 2023

Cost-minimization analysis of oral versus intravenous antibiotic treatment for Klebsiella pneumoniae liver abscess

by Yoong, Joanne, Yuen, Kah Hung, Molton, James S., Ding, Ying, Cher, Boon Piang, Chan, Monica, Kalimuddin, Shirin, Oon, Jolene, Young, Barnaby, Low, Jenny, Salada, Brenda M. A., Lee, Tau Hong, Wijaya, Li Min, Fisher, Dale, Izharuddin, Ezlyn, Wei, Yuan, Phillips, Rachel, Moorakonda, Rajesh, Lye, David C., Archuleta, Sophia
Published 2023

Cost-minimization analysis of oral versus intravenous antibiotic treatment for <i>Klebsiella pneumoniae</i> liver abscess

by Yoong, Joanne, Yuen, Kah Hung, Molton, James S, Ding, Ying, Cher, Boon Piang, Chan, Monica, Kalimuddin, Shirin, Oon, Jolene, Young, Barnaby, Low, Jenny, Salada, Brenda MA, Lee, Tau Hong, Wijaya, Li Min, Fisher, Dale, Izharuddin, Ezlyn, Wei, Yuan, Phillips, Rachel, Moorakonda, Rajesh, Lye, David C, Archuleta, Sophia
Published 2023