Comparison of diabetic and non-diabetic human leukocytic responses to different capsule types of klebsiella pneumoniae responsible for causing pyogenic liver abscess

• المؤلفون الرئيسيون: Lee, I. Russel, Sng, Ethel, Lee, Kok-Onn, Molton, James S., Chan, Monica, Kalimuddin, Shirin, Izharuddin, Ezlyn, Lye, David C., Archuleta, Sophia, Gan, Yunn-Hwen
• مؤلفون آخرون: Lee Kong Chian School of Medicine (LKCMedicine)
• التنسيق: مقال
• اللغة: English
• منشور في: 2018
• الموضوعات: Klebsiella Pneumoniae; Liver Abscess
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/86086; http://hdl.handle.net/10220/45377
• المؤسسة: Nanyang Technological University

The major risk factor for Klebsiella liver abscess (KLA) is type 2 diabetes mellitus (DM), but the immunological mechanisms involved in the increased susceptibility are poorly defined. We investigated the responses of neutrophils and peripheral blood mononuclear cells (PBMCs) to hypervirulent Klebsi...