Modulation of bacterial virulence and fitness by host glutathione

by Ku, Joanne WK, Gan, Yunn-Hwen
Published 2024

Short-chain fatty acids of various lengths differentially inhibit <i>Klebsiella pneumoniae</i> and <i>Enterobacteriaceae</i> species

by Chang, Kai Chirng, Nagarajan, Niranjan, Gan, Yunn-Hwen
Published 2024

Complement-activated vitronectin enhances the invasion of nonphagocytic cells by bacterial pathogens <i>Burkholderia</i> and <i>Klebsiella</i>

by Tan, Yi Han, Gamage, Akshamal M, Gan, Yunn-Hwen
Published 2024

Anti-Cancer Drug HMBA Acts as an Adjuvant during Intracellular Bacterial Infections by Inducing Type I IFN through STING

by Gamage, Akshamal Mihiranga, Lee, Kok-Onn, Gan, Yunn-Hwen
Published 2021

Cell envelope defects of different capsule-null mutants in K1 hypervirulent Klebsiella pneumoniae can affect bacterial pathogenesis

by Tan, Yi Han, Chen, Yahua, Chu, Wilson HW, Sham, Lok-To, Gan, Yunn-Hwen
Published 2022

Glutathione catabolism by Enterobacteriaceae species to hydrogen sulphide adversely affects the viability of host systems in the presence of 5 ' fluorodeoxyuridine

by Lim, Daniel Rui Xiang, Chen, Yahua, Ng, Li Fang, Gruber, Jan, Gan, Yunn-Hwen
Published 2023

Bacterium-Templated Polymer for Self-Selective Ablation of Multidrug-Resistant Bacteria

by Qi, Guobin, Hu, Fang, Kenry, Chong, Kok Chan, Wu, Min, Gan, Yunn Hwen, Liu, Bin
Published 2021

Bacterial-induced cell fusion is a danger signal triggering cGAS-STING pathway via micronuclei formation

by Ku, Joanne Wei Kay, Chen, Yahua, Lim, Bryan Jian Wei, Gasser, Stephan, Crasta, Karen Carmelina, Gan, Yunn-Hwen
Published 2022

Stool metagenome analysis of patients with Klebsiella pneumoniae liver abscess and their domestic partners

by Molton, James S., Lee, I. Russel, Bertrand, Denis, Ding, Ying, Kalimuddin, Shirin, Lye, David C., Nagarajan, Niranjan, Gan, Yunn-Hwen, Archuleta, Sophia
Published 2021

Stool metagenome analysis of patients with Klebsiella pneumoniae liver abscess and their domestic partners

by Molton, James S., Lee, I. Russel, Bertrand, Denis, Ding, Ying, Kalimuddin, Shirin, Lye, David C., Nagarajan, Niranjan, Gan, Yunn-Hwen, Archuleta, Sophia
Published 2022

Membrane potential-dependent uptake of cationic oligoimidazolium mediates bacterial DNA damage and death

by Yong, Melvin, Kok, Zhi Y., Koh, Chong Hui, Zhong, Wenbin, Ng, Justin T. Y., Mu, Yuguang, Chan-Park, Mary B., Gan, Yunn-Hwen
Published 2023

Membrane Potential-Dependent Uptake of Cationic Oligoimidazolium Mediates Bacterial DNA Damage and Death

by Yong, Melvin, Kok, Zhi Y, Koh, Chong H, Zhong, Wenbin, Ng, Justin TY, Mu, Yuguang, Chan-Park, Mary B, Gan, Yunn-Hwen
Published 2024

Acquisition of regulator on virulence plasmid of hypervirulent Klebsiella allows bacterial lifestyle switch in response to iron

by Chu, Wilson HW, Tan, Yi Han, Tan, Si Yin, Chen, Yahua, Yong, Melvin, Lye, David C, Kalimuddin, Shirin, Archuleta, Sophia, Gan, Yunn-Hwen
Published 2023

Comparison of diabetic and non-diabetic human leukocytic responses to different capsule types of klebsiella pneumoniae responsible for causing pyogenic liver abscess

by Lee, I. Russel, Sng, Ethel, Lee, Kok-Onn, Molton, James S., Chan, Monica, Kalimuddin, Shirin, Izharuddin, Ezlyn, Lye, David C., Archuleta, Sophia, Gan, Yunn-Hwen
Published 2018

A hydrophilic polyimidazolium antibiotic targeting the membranes of Gram-negative bacteria

by Chen, Yahua, Yong, Melvin, Li, Ming, Si, Zhangyong, Koh, Chong Hui, Lau, Pearlyn, Chang, Yi Wei, Teo, Jeanette, Chan-Park, Mary B., Gan, Yunn-Hwen
Published 2024

A hydrophilic polyimidazolium antibiotic targeting the membranes of Gram-negative bacteria

by Chen, Yahua, Yong, Melvin, Li, Ming, Si, Zhangyong, Koh, Chong Hui, Lau, Pearlyn, Chang, Yi Wei, Teo, Jeanette, Chan-Park, Mary B, Gan, Yunn-Hwen
Published 2024

A cationic main-chain poly(carbonate-imidazolium) potent against Mycobacterium abscessus and other resistant bacteria in mice

by Si, Zhangyong, Sun, Yan, Tan, Chongyun, Ooi, Ying Jie, Li, Ming, Raju, Cheerlavancha, Shubi, Jamal, Gan, Yunn-Hwen, Zhu, Yabin, Li, Peng, Chan-Park, Mary B., Pethe, Kevin
Published 2025

Copper-Nanoparticle-Coated Fabrics for Rapid and Sustained Antibacterial Activity Applications

by Goncalves, Rui A, Ku, Joanne WK, Zhang, Hao, Salim, Teddy, Oo, Guodong, Zinn, Alfred A, Boothroyd, Chris, Tang, Richard MY, Gan, Chee Lip, Gan, Yunn-Hwen, Lam, Yeng Ming
Published 2024

Extended loop region of Hcp1 is critical for the assembly and function of type VI secretion system in Burkholderia pseudomallei.

by Lim, Yan Ting, Jobichen, Chacko, Wong, Jocelyn, Direk Limmathurotsakul, ดิเรก ลิ้มมธุรสกุล, Li, Shaowei, Chen, Yahua, Raida, Manfred, Nalini Srinivasan, MacAry, Paul Anthony, Sivaraman, J., Gan, Yunn-Hwen
Published 2015

The proteobacterial species Burkholderia pseudomallei produces ergothioneine, which enhances virulence in mammalian infection

by Gamage, Akshamal M, Liao, Cangsong, Cheah, Irwin K, Chen, Yahua, Lim, Daniel RX, Ku, Joanne WK, Chee, Rhonda Sin Ling, Gengenbacher, Martin, Seebeck, Florian P, Halliwell, Barry, Gan, Yunn-Hwen
Published 2023