Therapeutic potential of promiscuous targets in Mycobacterium tuberculosis

بواسطة Lee, Bei Shi, Pethe, Kevin
منشور في 2020

Telacebec : an investigational antibacterial for the treatment of tuberculosis (TB)

بواسطة Lee, Bei Shi, Pethe, Kevin
منشور في 2022

Contribution of high-content imaging technologies to the development of anti-infective drugs

بواسطة Ang, Michelle Lay Teng, Pethe, Kevin
منشور في 2017

Targeting the cytochrome oxidases for drug development in mycobacteria

بواسطة Lee, Bei Shi, Sviriaeva, Ekaterina, Pethe, Kevin
منشور في 2020

Inhibiting respiration as a novel antibiotic strategy

بواسطة Lee, Bei Shi, Singh, Samsher, Pethe, Kevin
منشور في 2023

Chemical basis of combination therapy to combat antibiotic resistance

بواسطة Si, Zhangyong, Pethe, Kevin, Chan-Park, Mary B.
منشور في 2023

Oxidative phosphorylation — an update on a new, essential target space for drug discovery in mycobacterium tuberculosis

بواسطة Foo, Caroline Shi-Yan, Pethe, Kevin, Lupien, Andréanne
منشور في 2020

Novel targets and inhibitors of the Mycobacterium tuberculosis cytochrome bd oxidase to foster anti-tuberculosis drug discovery

بواسطة Harikishore, Amaravadhi, Mathiyazakan, Vikneswaran, Pethe, Kevin, Grüber, Gerhard
منشور في 2023

The Qcrb inhibitors TB47 and telacebec do not potentiate the activity of clofazimine in mycobacterium abscessus

بواسطة Sorayah, Ria, Moraski, Garret C., Barkan, Daniel, Pethe, Kevin
منشور في 2022

Features and functional importance of key residues of the Mycobacterium tuberculosis cytochrome bd oxidase

بواسطة Sviriaeva, Ekaterina, Manimekalai, Malathy Sony Subramanian, Grüber, Gerhard, Pethe, Kevin
منشور في 2021

Sensitivity of mycobacterium leprae to telacebec

بواسطة Lahiri, Ramanuj, Adams, Linda B., Thomas, Sangeeta Susan, Pethe, Kevin
منشور في 2022

Cryo-electron microscopy structure of the Mycobacterium tuberculosis cytochrome bcc:aa₃ supercomplex and a novel inhibitor targeting subunit cytochrome cI

بواسطة Mathiyazakan, Vikneswaran, Wong, Chui Fann, Harikishore, Amaravadhi, Pethe, Kevin, Grüber, Gerhard
منشور في 2023

Telacebec (Q203)-containing intermittent oral regimens sterilized mice infected with Mycobacterium ulcerans after only 16 doses

بواسطة Chauffour, Aurélie, Robert, Jérôme, Veziris, Nicolas, Aubry, Alexandra, Pethe, Kevin, Jarlier, Vincent
منشور في 2021

Toward a single-dose cure for buruli ulcer

بواسطة Thomas, Sangeeta Susan, Kalia, Nitin Pal, Ruf, Marie-Thérèse, Pluschke, Gerd, Pethe, Kevin
منشور في 2021

Cationic glycosylated block co-β-peptide acts on the cell wall of Gram-positive bacteria as anti-biofilm agents

بواسطة Zhang, Kaixi, Raju, Cheerlavancha, Zhong, Wenbin, Pethe, Kevin, Gründling, Angelika, Chan-Park, Mary B.
منشور في 2021

Bedaquiline Inhibits the ATP Synthase in Mycobacterium abscessus and Is Effective in Infected Zebrafish

بواسطة Dupont, Christian, Viljoen, Albertus, Thomas, Sangeeta, Roquet-Banères, Françoise, Herrmann, Jean-Louis, Pethe, Kevin, Kremer, Laurent
منشور في 2018

Isolation and characterization of a hybrid respiratory supercomplex consisting of Mycobacterium tuberculosis cytochrome bcc and Mycobacterium smegmatis cytochrome aa3

بواسطة Berry, Edward A., Huang, Li-Shar, Kim, Mi-Sun, Jang, Jichan, Pethe, Kevin, Nurlilah AB Rahman
منشور في 2018

Naturally-occurring polymorphisms in QcrB are responsible for resistance to Telacebec in Mycobacterium abscessus

بواسطة Sorayah, Ria, Manimekalai, Malathy Sony Subramanian, Shin, Sung Jae, Koh, Won-Jung, Grüber, Gerhard, Pethe, Kevin
منشور في 2021

Inhibitors of energy metabolism interfere with antibiotic-induced death in mycobacteria

بواسطة Lee, Bei Shi, Kalia, Nitin Pal, Jin, Xin Er F., Hasenoehrl, Erik J., Berney, Michael, Pethe, Kevin
منشور في 2019

Carbon metabolism modulates the efficacy of drugs targeting the cytochrome bc1:aa3 in Mycobacterium tuberculosis

بواسطة Moraski, Garrett C., Miller, Marvin J., Pethe, Kevin, Kalia, Nitin Pal, Lee, Bei Shi, Nurlilah Ab Rahman
منشور في 2019