Toward a single-dose cure for buruli ulcer

A single dose of Q203 (Telacebec), a phase 2 clinical candidate for tuberculosis, eradicates Mycobacterium ulcerans in a mouse model of Buruli ulcer infection without relapse up to 19 weeks posttreatment. Clinical use of Q203 may dramatically simplify the clinical management of Buruli ulcer, a negle...

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Bibliographic Details
Main Authors: Thomas, Sangeeta Susan, Kalia, Nitin Pal, Ruf, Marie-Thérèse, Pluschke, Gerd, Pethe, Kevin
Other Authors: Interdisciplinary Graduate School (IGS)
Format: Article
Language:English
Published: 2021
Subjects:
Online Access:https://hdl.handle.net/10356/148927
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Institution: Nanyang Technological University
Language: English