Toward a single-dose cure for buruli ulcer

by Thomas, Sangeeta Susan, Kalia, Nitin Pal, Ruf, Marie-Thérèse, Pluschke, Gerd, Pethe, Kevin
Published 2021

Inhibitors of energy metabolism interfere with antibiotic-induced death in mycobacteria

by Lee, Bei Shi, Kalia, Nitin Pal, Jin, Xin Er F., Hasenoehrl, Erik J., Berney, Michael, Pethe, Kevin
Published 2019

Carbon metabolism modulates the efficacy of drugs targeting the cytochrome bc1:aa3 in Mycobacterium tuberculosis

by Moraski, Garrett C., Miller, Marvin J., Pethe, Kevin, Kalia, Nitin Pal, Lee, Bei Shi, Nurlilah Ab Rahman
Published 2019

M. tuberculosis relies on trace oxygen to maintain energy homeostasis and survive in hypoxic environments

by Kalia, Nitin Pal, Singh, Samsher, Hards, Kiel, Cheung, Chen-Yi, Sviriaeva, Ekaterina, Banaei-Esfahani, Amir, Aebersold, Ruedi, Berney, Michael, Cook, Gregory M., Pethe, Kevin
Published 2023

Exploiting the synthetic lethality between terminal respiratory oxidases to kill Mycobacterium tuberculosis and clear host infection

by Hasenoehrl, Erik J., Koh, Vanessa H., Ang, Michelle L. T., Sajorda, Dannah R., Hards, Kiel, Grüber, Gerhard, Alonso, Sylvie, Cook, Gregory M., Berney, Michael, Pethe, Kevin, Kalia, Nitin Pal, Ab Rahman, Nurlilah Binte
Published 2017

GaMF1.39’s antibiotic efficacy and its enhanced antitubercular activity in combination with Clofazimine, Telacebec, ND-011992 or TBAJ-876

by Ragunathan, Priya, Ng, Pearly Shuyi, Singh, Samsher, Poh, Wee Han, Litty, Dennis, Kalia, Nitin Pal, Larsson, Simon, Harikishore, Amaravadhi, Rice, Scott A., Ingham, Philip William, Müller, Volker, Moraski, Garrett, Miller, Marvin J., Dick, Thomas, Pethe, Kevin, Grüber, Gerhard
Published 2023

Discovery of a novel mycobacterial F-ATP synthase inhibitor and its potency in combination with diarylquinolines

by Hotra, Adam, Ragunathan, Priya, Ng, Pearly Shuyi, Seankongsuk, Pattarakiat, Harikishore, Amaravadhi, Sarathy, Jickky Palmae, Saw, Wuan-Geok, Lakshmanan, Umayal, Sae-Lao, Patcharaporn, Kalia, Nitin Pal, Shin, Joon, Kalyanasundaram, Revathy, Anbarasu, Sivaraj, Parthasarathy, Krupakar, Pradeep, Chaudhari Namrata, Makhija, Harshyaa, Dröge, Peter, Poulsen, Anders, Tan, Jocelyn Hui Ling, Pethe, Kevin, Dick, Thomas, Bates, Roderick Wayland, Grüber, Gerhard
Published 2021

Dual inhibition of the terminal oxidases eradicates antibiotic-tolerant Mycobacterium tuberculosis

by Lee, Bei Shi, Hards, Kiel, Engelhart, Curtis A., Hasenoehrl, Erik J., Kalia, Nitin Pal, Mackenzie, Jared S., Sviriaeva, Ekaterina, Chong, Sherilyn Shi Min, Manimekalai, Malathy Sony S., Koh, Vanessa H., Chan, John, Xu, Jiayong, Alonso, Sylvie, Miller, Marvin J., Steyn, Adrie J. C., Grüber, Gerhard, Schnappinger, Dirk, Berney, Michael, Cook, Gregory M., Moraski, Garrett C., Pethe, Kevin
Published 2021