Carbon metabolism modulates the efficacy of drugs targeting the cytochrome bc1:aa3 in Mycobacterium tuberculosis

The influence of carbon metabolism on oxidative phosphorylation is poorly understood in mycobacteria. M. tuberculosis expresses two respiratory terminal oxidases, the cytochrome bc1:aa3 and the cytochrome bd oxidase, which are jointly required for oxidative phosphorylation and mycobacterial viabilit...

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Bibliographic Details
Main Authors: Moraski, Garrett C., Miller, Marvin J., Pethe, Kevin, Kalia, Nitin Pal, Lee, Bei Shi, Nurlilah Ab Rahman
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/10356/89857
http://hdl.handle.net/10220/49328
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Institution: Nanyang Technological University
Language: English