Pretomanid is a dual inhibitor of the cytochrome bcc:aa3 and cytochrome bd oxidase that synergizes with Q203 to eradicate Mycobacterium tuberculosis

• Main Author: Nurlilah Ab Rahman
• Other Authors: Kevin Pethe
• Format: Thesis-Master by Research
• Language: English
• Published: Nanyang Technological University 2022
• Subjects: Science::Biological sciences::Microbiology::Bacteria; Science::Biological sciences::Microbiology::Drug Resistance; Science::Biological sciences::Biochemistry
• Online Access: https://hdl.handle.net/10356/160530
• Institution: Nanyang Technological University

Tuberculosis is a global disease that carries with it high health and socio-economic burdens onto populations. Millions of people come down with the active form of the disease every year but the proportion of the world population that carries the latent form of this disease is believed to around...