Syntheses and structure–activity relationships of N-phenethyl-quinazolin-4-yl-amines as potent inhibitors of cytochrome bd oxidase in Mycobacterium tuberculosis

Syntheses and structure–activity relationships of N-phenethyl-quinazolin-4-yl-amines as potent inhibitors of cytochrome bd oxidase in Mycobacterium tuberculosis

The development of cytochrome bd oxidase (cyt‐bd) inhibitors are needed for comprehensive termination of energy production in Mycobacterium tuberculosis (Mtb) to treat tuberculosis infections. Herein, we report on the structure‐activity‐relationships (SAR) of 22 new N‐phenethyl‐quinazolin‐4‐ yl‐amin...

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Bibliographic Details
Main Authors: Hopfner, Sarah M., Lee, Bei Shi, Kalia, Nitin P., Miller Marvin J., Pethe, Kevin, Moraski, Garrett C.
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2022
Subjects:
Science::Biological sciences
Tuberculosis
Drug Development
Online Access:https://hdl.handle.net/10356/153933
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/153933

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