Novel targets and inhibitors of the Mycobacterium tuberculosis cytochrome bd oxidase to foster anti-tuberculosis drug discovery

Novel targets and inhibitors of the Mycobacterium tuberculosis cytochrome bd oxidase to foster anti-tuberculosis drug discovery

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), is the most devastating bacterial disease. Multidrug-resistant Mtb strains are spreading worldwide, underscoring the need for new anti-TB targets and inhibitors. The respiratory chain complexes, including the cytochrome bd oxidase (cyt-b...

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Bibliographic Details
Main Authors: Harikishore, Amaravadhi, Mathiyazakan, Vikneswaran, Pethe, Kevin, Grüber, Gerhard
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2023
Subjects:
Medicine, Health and Life Sciences
Cytochrome bd oxidase
Virulence
Mycobacteria
Tuberculosis
Online Access:https://hdl.handle.net/10356/169255
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/169255

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