The higher prevalence of extended spectrum beta-lactamases among Escherichia coli ST131 in Southeast Asia is driven by expansion of a single, locally prevalent subclone

• Main Authors: Chen, Swaine Lin, Ding, Ying, Apisarnthanarak, Anucha, Kalimuddin, Shirin, Archuleta, Sophia, Sharifah Faridah Syed Omar, De, Partha Pratim, Koh, Tse Hsien, Chew, Kean Lee, Nadia Atiya, Suwantarat, Nuntra, Velayuthan, Rukumani Devi, Wong, Joshua Guo Xian, Lye, David C.
• Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
• Format: Article
• Language: English
• Published: 2020
• Subjects: Science::Medicine; Escherichia Coli; ST131 Multilocus Sequence Type (MLST)
• Online Access: https://hdl.handle.net/10356/142340
• Institution: Nanyang Technological University

The ST131 multilocus sequence type (MLST) of Escherichia coli is a globally successful pathogen whose dissemination is increasing rates of antibiotic resistance. Numerous global surveys have demonstrated the pervasiveness of this clone; in some regions ST131 accounts for up to 30% of all E. coli iso...