An experimental medicine decipher of a minimum correlate of cellular immunity: Study protocol for a double-blind randomized controlled trial

by Kalimuddin, Shirin, Chan, Yvonne FZ, Sessions, October M, Chan, Kuan Rong, Ong, Eugenia Z, Low, Jenny G, Bertoletti, Antonio, Ooi, Eng Eong
Published 2023

Temporal dynamics of the host molecular responses underlying severe COVID-19 progression and disease resolution

by Ong, Eugenia Z., Kalimuddin, Shirin, Chia, Wen Chong, Ooi, Sarah H., Koh, Clara Wt, Tan, Hwee Cheng, Zhang, Summer L., Low, Jenny G., Ooi, Eng Eong, Chan, Kuan Rong
Published 2022

18F-fluorodeoxyglucose positron emission tomography as a window into human dengue pathophysiology

by Kalimuddin, Shirin, Xie, Wanying, Watanabe, Satoru, Tham, Jing Yang, Sam, Huizhen, Chan, Kitti Wing Ki, Yap, Tiang Siew, Totman, John J., Chacko, Ann-Marie, Vasudevan, Subhash G., Low, Jenny G.
Published 2022

The effectiveness of public health interventions against COVID-19: Lessons from the Singapore experience

by Ansah, John P., Matchar, David Bruce, Shao Wei, Sean Lam, Low, Jenny G., Pourghaderi, Ahmad Reza, Siddiqui, Fahad Javaid, Min, Tessa Lui Shi, Wei-Yan, Aloysius Chia, Ong, Marcus Eng Hock
Published 2022

Dengue virus activates polyreactive, natural IgG B cells after primary and secondary infection

by Balakrishnan, Thavamalar, Bela-ong, Dennis B., Toh, Ying Xiu, Flamand, Marie, Devi, Shamala, Koh, Mickey B., Hibberd, Martin L., Ooi, Eng Eong, Low, Jenny G., Leo, Yee Sin, Gu, Feng, Fink, Katja
Published 2011

Predictors and Clinical Outcomes of Poor Platelet Recovery in Adult Dengue With Thrombocytopenia: A Multicenter, Prospective Study

by Archuleta, Sophia, Chia, Po Ying, Wei, Yuan, Syed-Omar, Sharifah F, Low, Jenny G, Oh, Helen M, Fisher, Dale, Ponnampalavanar, Sasheela SL, Wijaya, Limin, Kamarulzaman, Adeeba, Lum, Lucy CS, Tambyah, Paul A, Leo, Yee-Sin, Lye, David C
Published 2022

RNase2 is a possible trigger of acute-on-chronic inflammation leading to mRNA vaccine-associated cardiac complication.

by Ong, Eugenia Z, Koh, Clara WT, Tng, Danny JH, Ooi, Justin SG, Yee, Jia Xin, Chew, Valerie SY, Leong, Yan Shan, Gunasegaran, Kurugulasigamoney, Yeo, Chin Pin, Oon, Lynette LE, Sim, Jean XY, Chan, Kuan Rong, Low, Jenny G, Ooi, Eng Eong
Published 2023

Prophylactic platelet transfusion plus supportive care versus supportive care alone in adults with dengue and thrombocytopenia: a multicentre, open-label, randomised, superiority t...

by Lye, David C, Archuleta, Sophia, Syed-Omar, Sharifah F, Low, Jenny G, Oh, Helen M, Wei, Yuan, Fisher, Dale, Ponnampalavanar, Sasheela SL, Wijaya, Limin, Lee, Linda K, Ooi, Eng-Eong, Kamarulzaman, Adeeba, Lum, Lucy C, Tambyah, Paul A, Leo, Yee-Sin
Published 2022

Mimicking immune signatures of flavivirus infection with targeted adjuvants improves dengue subunit vaccine immunogenicity

by Bidet, Katell, Ho, Victor, Chu, Collins Wenhan, Ahmad Nazri Mohamed Naim, Thazin, Khaing, Chan, Kuan Rong, Low, Jenny G. H., Choy, Milly M., Wong, Lan Hiong, de Sessions, Paola Florez, Lee, Yie Hou, Hibberd, Martin L., Ooi, Eng Eong, Fink, Katja, Chen, Jianzhu
Published 2020

Early induction of functional SARS-CoV-2-specific T cells associates with rapid viral clearance and mild disease in COVID-19 patients

by Tan, Anthony T., Linster, Martin, Tan, Chee Wah, Le Bert, Nina, Chia, Wan Ni, Kunasegaran, Kamini, Zhuang, Yan, Tham, Christine Y. L., Chia, Adeline, Smith, Gavin J. D., Young, Barnaby, Kalimuddin, Shirin, Low, Jenny G. H., Lye, David, Wang, Lin-Fa, Bertoletti, Antonio
Published 2022

Gut Ruminococcaceae levels at baseline correlate with risk of antibiotic-associated diarrhea

by Gu, Xiaoqiong, Sim, Jean X. Y., Lee, Wei Lin, Cui, Liang, Chan, Yvonne F. Z., Chang, Ega Danu, Teh, Yii Ean, Zhang, An-Ni, Armas, Federica, Chandra, Franciscus, Chen, Hongjie, Zhao, Shijie, Lee, Zhanyi, Thompson, Janelle, Ooi, Eng Eong, Low, Jenny G., Alm, Eric J., Kalimuddin, Shirin
Published 2023

A phase I/II randomized, double-blinded, placebo-controlled trial of a self-amplifying Covid-19 mRNA vaccine

by Low, Jenny G., de Alwis, Ruklanthi, Chen, Shiwei, Kalimuddin, Shirin, Leong, Yan Shan, Mah, Tania Ken Lin, Yuen, Natalene, Tan, Hwee Cheng, Zhang, Summer L., Sim, Jean X. Y., Chan, Yvonne F. Z., Syenina, Ayesa, Yee, Jia Xin, Ong, Eugenia Z., Sekulovich, Rose, Sullivan, Brian B., Lindert, Kelly, Sullivan, Sean M., Chivukula, Pad, Hughes, Steven G., Ooi, Eng Eong
Published 2023

Oral vs Intravenous Antibiotics for Patients With Klebsiella pneumoniae Liver Abscess: A Randomized, Controlled Noninferiority Study

by Molton, James S, Chan, Monica, Kalimuddin, Shirin, Oon, Jolene, Young, Barnaby E, Low, Jenny G, Salada, Brenda MA, Lee, Tau Hong, Wijaya, Limin, Fisher, Dale A, Izharuddin, Ezlyn, Koh, Tse Hsien, Teo, Jeanette WP, Krishnan, Prabha Unny, Tan, Bien Peng, Woon, Winston WL, Ding, Ying, Wei, Yuan, Phillips, Rachel, Moorakonda, Rajesh, Yuen, Kah Hung, Cher, Boon Piang, Yoong, Joanne, Lye, David C, Archuleta, Sophia
Published 2021

Viral dynamics and immune correlates of coronavirus disease 2019 (COVID-19) severity

by Young, Barnaby Edward, Ong, Sean W. X., Ng, Lisa F. P., Anderson, Danielle E., Chia, Wan Ni, Chia, Po Ying, Ang, Li Wei, Mak, Tze-Minn, Kalimuddin, Shirin, Chai, Louis Yi Ann, Pada, Surinder, Tan, Seow Yen, Sun, Louisa, Parthasarathy, Purnima, Fong, Siew-Wai, Chan, Yi-Hao, Tan, Chee Wah, Lee, Bernett, Rötzschke, Olaf, Ding, Ying, Tambyah, Paul, Low, Jenny G. H., Cui, Lin, Barkham, Timothy, Lin, Raymond Tzer Pin, Leo, Yee Sin, Renia, Laurent, Wang, Lin-Fa, Lye, David Chien
Published 2022

The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the optimal therapeut...

by Chan, Conrad E. Z., Seah, Shirley G. K., Chye, De Hoe, Massey, Shane, Torres, Maricela, Lim, Angeline P. C., Wong, Steven K. K., Neo, Jacklyn J. Y., Wong, Pui San, Lim, Jie Hui, Loh, Gary S. L., Wang, Dongling, Boyd-Kirkup, Jerome D., Guan, Siyu, Thakkar, Dipti, Teo, Guo Hui, Purushotorman, Kiren, Hutchinson, Paul E., Young, Barnaby E., Low, Jenny G., MacAry, Paul A., Hentze, Hannes, Prativadibhayankara, Venkateshan S., Ethirajulu, Kantharaj, Comer, Jason E., Tseng, Chien-Te K., Barrett, Alan D. T., Ingram, Piers J., Brasel, Trevor, Hanson, Brendon John
Published 2022