The Divergent Immunomodulatory Effects of Short Chain Fatty Acids and Medium Chain Fatty Acids

by Sam, Qi Hui, Ling, Hua, Yew, Wen Shan, Tan, Zhaohong, Ravikumar, Sharada, Chang, Matthew Wook, Chai, Louis Yi Ann
Published 2022

A Novel X-Linked Inhibitor of Apoptosis Deficient Variant Showing Attenuated Epstein-Barr Virus Response

by Zhong, Youjia, Huang, Chiung-Hui, Soe, Win Mar, Chan, Koon Wing, Isa, Mas Suhaila, Soh, Jianyi, Yap, Mark, MacAry, Paul Anthony, Lau, Yu-Lung, Chai, Louis Yi Ann, Shek, Lynette Pei-Chi, Lee, Bee Wah
Published 2023

When to Test for Anti-Interferon-gamma Autoantibody?

by Loh, Kent Mun, Zhong, Youjia, Lin, Li, Chan, Monica, Cherng, Benjamin Pei Zhi, Yew, Haur Sen, Sun, Haoyang, Dickens, Borame Sue Lee, Lye, David Chien Boon, Huang, Chiung Hui, Khoo, Ai Leng, Chai, Louis Yi Ann
Published 2023

Efficacy of covid-19 vaccines in immunocompromised patients: systematic review and meta-analysis

by Bin Lee, Ainsley Ryan Yan, Wong, Shi Yin, Chai, Louis Yi Ann, Lee, Soo Chin, Lee, Matilda Xinwei, Muthiah, Mark Dhinesh, Tay, Sen Hee, Teo, Chong Boon, Tan, Benjamin Kye Jyn, Chan, Yiong Huak, Sundar, Raghav, Soon, Yu Yang
Published 2022

Simple "Rule-of-6" Predicts Severe Coronavirus Disease 2019 (COVID-19)

by Dickens, Borame Sue Lee, Lim, Jue Tao, Low, Jere Wenn, Lee, Chun Kiat, Sun, Yinxiaohe, Nasir, Haziq Bin Mohamad, Akramullah, Farheen Akram Bte Mohamed, Yan, Gabriel, Oon, Jolene, Yan, Benedict, Sun, Louisa, Cook, Alex R, Tambyah, Paul Anantharajah, Chai, Louis Yi Ann
Published 2021

IDentif.AI-Omicron: Harnessing an AI-Derived and Disease-Agnostic Platform to Pinpoint Combinatorial Therapies for Clinically Actionable Anti-SARS-CoV-2 Intervention

by Blasiak, Agata, Truong, Anh TL, Wang, Peter, Hooi, Lissa, Chye, De Hoe, Tan, Shi-Bei, You, Kui, Remus, Alexandria, Allen, David Michael, Chai, Louis Yi Ann, Chan, Conrad EZ, Lye, David CB, Tan, Gek-Yen G, Seah, Shirley GK, Chow, Edward Kai-Hua, Ho, Dean
Published 2022

Virological and serological kinetics of SARS-CoV-2 Delta variant vaccine breakthrough infections: a multicentre cohort study

by Chia, Po Ying, Ong, Sean Wei Xiang, Chiew, Calvin J., Ang, Li Wei, Chavatte, Jean-Marc, Mak, Tze-Minn, Cui, Lin, Kalimuddin, Shirin, Chia, Wan Ni, Tan, Chee Wah, Chai, Louis Yi Ann, Tan, Seow Yen, Zheng, Shuwei, Lin, Raymond Tzer Pin, Wang, Linfa, Leo, Yee Sin, Lee, Vernon J., Lye, David C., Young, Barnaby Edward
Published 2022

COVID-19 Severity and Waning Immunity After up to 4 mRNA Vaccine Doses in 73 608 Patients With Cancer and 621 475 Matched Controls in Singapore A Nationwide Cohort Study

by Tan, Wei Chong, Tan, Janice Yu Jin, Lim, Joline Si Jing, Tan, Ryan Ying Cong, Lee, Ainsley Ryan Yan Bin, Leong, Fun Loon, Lee, Soo Chin, Chai, Louis Yi Ann, Tan, Thuan Tong, Malek, Muhammad Ismail Bin Abdul, Ong, Benjamin, Lye, David Chien, Chiew, Calvin J, Chng, Wee Joo, Lim, Soon Thye, Bharwani, Lavina D, Tan, Iain Beehuat, Sundar, Raghav, Tan, Kelvin Bryan
Published 2023

Longitudinal single cell atlas identifies complex temporal relationship between type I interferon response and COVID-19 severity

by Lin, Quy Xiao Xuan, Rajagopalan, Deepa, Gamage, Akshamal M., Tan, Le Min, Venkatesh, Prasanna Nori, Chan, Wharton O. Y., Kumar, Dilip, Agrawal, Ragini, Chen, Yao, Fong, Siew-Wai, Singh, Amit, Sun, Louisa J., Tan, Seow-Yen, Chai, Louis Yi Ann, Somani, Jyoti, Lee, Bernett, Renia, Laurent, Ng, Lisa F. P., Ramanathan, Kollengode, Wang, Lin-Fa, Young, Barnaby, Lye, David, Singhal, Amit, Prabhakar, Shyam
Published 2024

The IDentif.AI-x pandemic readiness platform: rapid prioritization of optimized COVID-19 combination therapy regimens

by Blasiak, Agata, Truong, Anh T. L., Remus, Alexandria, Hooi, Lissa, Seah, Shirley Gek Kheng, Wang, Peter, Chye, De Hoe, Lim, Angeline Pei Chiew, Ng, Kim Tien, Teo, Swee Teng, Tan, Yee-Joo, Allen, David Michael, Chai, Louis Yi Ann, Chng, Wee Joo, Lin, Raymond T. P., Lye, David C., Wong, John Eu-Li, Tan, Gladys Gek-Yen, Chan, Conrad En Zuo, Chow, Edward Kai-Hua, Ho, Dean
Published 2023

COVID-19 severity and waning immunity after up to 4 mRNA vaccine doses in 73 608 patients with cancer and 621 475 matched controls in Singapore: a nationwide cohort study

by Tan, Wei Chong, Tan, Janice Yu Jin, Lim, Joline Si Jing, Tan, Ryan Ying Cong, Lee, Ainsley Ryan Yan Bin, Leong, Fun Loon, Lee, Soo Chin, Chai, Louis Yi Ann, Tan, Thuan Tong, Muhammad Ismail Bin Abdul Malek, Ong, Benjamin, Lye, David C., Chiew, Calvin J., Chng, Wee Joo, Lim, Soon Thye, Bharwani, Lavina D., Tan, Iain Bee Huat, Sundar, Raghav, Tan, Kelvin Bryan
Published 2024

The IDentif.AI-x pandemic readiness platform: Rapid prioritization of optimized COVID-19 combination therapy regimens.

by Blasiak, Agata, Truong, Anh TL, Remus, Alexandria, Hooi, Lissa, Seah, Shirley Gek Kheng, Wang, Peter, Chye, De Hoe, Lim, Angeline Pei Chiew, Ng, Kim Tien, Teo, Swee Teng, Tan, Yee-Joo, Allen, David Michael, Chai, Louis Yi Ann, Chng, Wee Joo, Lin, Raymond TP, Lye, David CB, Wong, John Eu-Li, Tan, Gek-Yen Gladys, Chan, Conrad En Zuo, Chow, Edward Kai-Hua, Ho, Dean
Published 2022

Clinical features and predictors of severity in COVID-19 patients with critical illness in Singapore

by Puah, Ser Hon, Young, Barnaby Edward, Chia, Po Ying, Ho, Vui Kian, Loh, Jiashen, Gokhale, Roshni Sadashiv, Tan, Seow Yen, Sewa, Duu Wen, Kalimuddin, Shirin, Tan, Chee Keat, Pada, Surinder KMS, Cove, Matthew Edward, Chai, Louis Yi Ann, Parthasarathy, Purnima, Ho, Benjamin Choon Heng, Ng, Jensen Jiansheng, Ling, Li Min, Abisheganaden, John A, Lee, Vernon JM, Tan, Cher Heng, Lin, Raymond TP, Leo, Yee Sin, Lye, David C, Yeo, Tsin Wen
Published 2021

Clinical features and predictors of severity in COVID-19 patients with critical illness in Singapore.

by Ser Hon Puah, Puah, Ser Hon, Young, Barnaby Edward, Chia, Po Ying, Ho, Vui Kian, Loh, Jiashen, Gokhale, Roshni Sadashiv, Tan, Seow Yen, Sewa, Duu Wen, Kalimuddin, Shirin, Tan, Chee Keat, Pada, Surinder KMS, Cove, Matthew Edward, Chai, Louis Yi Ann, Parthasarathy, Purnima, Ho, Benjamin Choon Heng, Ng, Jensen Jiansheng, Ling, Li Min, Abisheganaden, John A, Lee, Vernon JM, Tan, Cher Heng, Lin, Raymond TP, Leo, Yee Sin, Lye, David C, Yeo, Tsin Wen
Published 2021

Viral dynamics and immune correlates of coronavirus disease 2019 (COVID-19) severity

by Young, Barnaby Edward, Ong, Sean W. X., Ng, Lisa F. P., Anderson, Danielle E., Chia, Wan Ni, Chia, Po Ying, Ang, Li Wei, Mak, Tze-Minn, Kalimuddin, Shirin, Chai, Louis Yi Ann, Pada, Surinder, Tan, Seow Yen, Sun, Louisa, Parthasarathy, Purnima, Fong, Siew-Wai, Chan, Yi-Hao, Tan, Chee Wah, Lee, Bernett, Rötzschke, Olaf, Ding, Ying, Tambyah, Paul, Low, Jenny G. H., Cui, Lin, Barkham, Timothy, Lin, Raymond Tzer Pin, Leo, Yee Sin, Renia, Laurent, Wang, Lin-Fa, Lye, David Chien
Published 2022

Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study

by Young, Barnaby E, Fong, Siew-Wai, Chan, Yi-Hao, Mak, Tze-Minn, Ang, Li Wei, Anderson, Danielle E, Lee, Cheryl Yi-Pin, Amrun, Siti Naqiah, Lee, Bernett, Goh, Yun Shan, Su, Yvonne CF, Wei, Wycliffe E, Kalimuddin, Shirin, Chai, Louis Yi Ann, Pada, Surinder, Tan, Seow Yen, Sun, Louisa, Parthasarathy, Purnima, Chen, Yuan Yi Constance, Barkham, Timothy, Lin, Raymond Tzer Pin, Maurer-Stroh, Sebastian, Leo, Yee-Sin, Wang, Lin-Fa, Renia, Laurent, Lee, Vernon J, Smith, Gavin JD, Lye, David Chien, Ng, Lisa FP
Published 2021

Viral Dynamics and Immune Correlates of Coronavirus Disease 2019 (COVID-19) Severity.

by Young, Barnaby E, Ong, Sean WX, Ng, Lisa FP, Anderson, Danielle E, Chia, Wan Ni, Chia, Po Ying, Ang, Li Wei, Mak, Tze-Minn, Kalimuddin, Shirin, Chai, Louis Yi Ann, Pada, Surinder, Tan, Seow Yen, Sun, Louisa, Parthasarathy, Purnima, Fong, Siew-Wai, Chan, Yi-Hao, Tan, Chee Wah, Lee, Bernett, Rötzschke Olaf, Ding, Ying, Tambyah, Paul, Low, Jenny GH, Cui, Lin, Barkham, Timothy, Lin, Raymond Tzer Pin, Leo, Yee-Sin, Renia, Laurent, Wang, Lin-Fa, Lye, David Chien, Singapore 2019 Novel Coronavirus Outbreak Research Team
Published 2021