IDentif.AI: Rapidly optimizing combination therapy design against severe Acute Respiratory Syndrome Coronavirus 2 (SARS-Cov-2) with digital drug development

by Blasiak, Agata, Lim, Jhin Jieh, Seah, Shirley Gek Kheng, Kee, Theodore, Remus, Alexandria, Chye, De Hoe, Wong, Pui San, Hooi, Lissa, Truong, Anh T. L., Le, Nguyen, Chan, Conrad E. Z., Desai, Rishi, Ding, Xianting, Hanson, Brendon J., Chow, Edward Kai-Hua, Ho, Dean
Published 2022

Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01

by Gu, Yue, Wong, Yee Hwa, Liew, Chong Wai, Chan, Conrad E. Z., Murali, Tanusya M., Yap, Jiawei, Too, Chien Tei, Purushotorman, Kiren, Hamidinia, Maryam, El Sahili, Abbas, Goh, Angeline T. H., Teo, Rachel Z. C., Wood, Kathryn J., Hanson, Brendon J., Gascoigne, Nicholas R. J., Lescar, Julien, Vathsala, Anantharaman, MacAry, Paul A.
Published 2019

The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the optimal therapeut...

by Chan, Conrad E. Z., Seah, Shirley G. K., Chye, De Hoe, Massey, Shane, Torres, Maricela, Lim, Angeline P. C., Wong, Steven K. K., Neo, Jacklyn J. Y., Wong, Pui San, Lim, Jie Hui, Loh, Gary S. L., Wang, Dongling, Boyd-Kirkup, Jerome D., Guan, Siyu, Thakkar, Dipti, Teo, Guo Hui, Purushotorman, Kiren, Hutchinson, Paul E., Young, Barnaby E., Low, Jenny G., MacAry, Paul A., Hentze, Hannes, Prativadibhayankara, Venkateshan S., Ethirajulu, Kantharaj, Comer, Jason E., Tseng, Chien-Te K., Barrett, Alan D. T., Ingram, Piers J., Brasel, Trevor, Hanson, Brendon John
Published 2022