Dengue Virus Non-Structural Protein 5

by El Sahili, Abbas, Lescar, Julien
Published 2018

On the design of a constitutively active peptide asparaginyl ligase for facile protein conjugation

by Chua, Niying, Wong, Yee Hwa, El Sahili, Abbas, Liu, Chuan Fa, Lescar, Julien
Published 2023

Identification and structural validation of purine nucleoside phosphorylase from Plasmodium falciparum as a target of MMV000848

by Chung, Zara, Lin, Jianqing, Wirjanata, Grennady, Dziekan, Jerzy Michal, El Sahili, Abbas, Preiser, Peter Rainer, Bozdech, Zbynek, Lescar, Julien
Published 2024

The protein kinase CK2 catalytic domain from Plasmodium falciparum : crystal structure, tyrosine kinase activity and inhibition

by Ruiz-Carrillo, David, Lin, Jianqing, El Sahili, Abbas, Wei, Meng, Sze, Siu Kwan, Doerig, Christian, Lescar, Julien, Cheung, Peter Ching For
Published 2018

Functional Evolution in Orthologous Cell-encoded RNA-dependent RNA Polymerases

by Qian, Xinlei, Hamid, Fursham M., El Sahili, Abbas, Darwis, Dina Amallia, Wong, Yee Hwa, Bhushan, Shashi, Makeyev, Eugene V., Lescar, Julien
Published 2016

Crystal structures of full length DENV4 NS2B-NS3 reveal the dynamic interaction between NS2B and NS3

by Phoo, Wint Wint, El Sahili, Abbas, Zhang, ZhenZhen, Chen, Ming Wei, Liew, Chong Wai, Lescar, Julien, Vasudevan, Subhash G., Luo, Dahai
Published 2022

NS5 from dengue virus serotype 2 can adopt a conformation analogous to that of its Zika virus and Japanese encephalitis virus homologues

by El Sahili, Abbas, Soh, Sherryl Tingjin, Schiltz, Jonas, Gharbi-Ayachi, Aïcha, Seh, Cheah Chen, Shi, Pei-Yong, Lim, Siew Pheng, Lescar, Julien
Published 2020

Novel phage lysin Abp013 against Acinetobacter baumannii

by Chu, Joash Jun Keat, Poh, Wee Han, Nabilah Taqiah Hasnuddin, Hew, En Yi, Dam, Linh Chi, El Sahili, Abbas, Rice, Scott A., Goh, Boon Chong
Published 2022

Non-nucleoside inhibitors of Zika virus RNA-dependent RNA polymerase

by Gharbi-Ayachi, Aïcha, Santhanakrishnan, Sridhar, Wong, Yee Hwa, Chan, Kitti Wing Ki, Tan, Siok Thing, Bates, Roderick Wayland, Vasudevan, Subhash G., El Sahili, Abbas, Lescar, Julien
Published 2020

The SiaABC threonine phosphorylation pathway controls biofilm formation in response to carbon availability in Pseudomonas aeruginosa

by Poh, Wee Han, Lin, Jianqing, Colley, Brendan, Müller, Nicolai, Goh, Boon Chong, Schleheck, David, El Sahili, Abbas, Marquardt, Andreas, Liang, Yang, Kjelleberg, Staffan, Lescar, Julien, Rice, Scott A., Klebensberger, Janosch
Published 2021

Turning an asparaginyl endopeptidase into a peptide ligase

by Hemu, Xinya, El Sahili, Abbas, Hu, Side, Zhang, Xiaohong, Serra, Aida, Goh, Boon Chong, Darwis, Dina Amallia, Chen, Ming Wei, Sze, Siu Kwan, Liu, Chuan-Fa, Lescar, Julien, Tam, James P.
Published 2021

Pyruvate kinase regulates the pentose-phosphate pathway in response to hypoxia in mycobacterium tuberculosis

by Zhong, Wenhe, Guo, Jingjing, Cui, Liang, Chionh, Yok Hian, Li, Kuohan, El Sahili, Abbas, Cai, Qixu, Yuan, Meng, Michels, Paul A. M., Fothergill-Gilmore, Linda A., Walkinshaw, Malcolm D., Mu, Yuguang, Lescar, Julien, Dedon, Peter C.
Published 2021

Structural determinants for peptide-bond formation by asparaginyl ligases

by Hemu, Xinya, El Sahili, Abbas, Hu, Side, Wong, Kaho, Chen, Yu, Wong, Yee Hwa, Zhang, Xiaohong, Serra, Aida, Goh, Boon Chong, Darwis, Dina Amallia, Chen, Ming Wei, Sze, Siu Kwan, Liu, Chuan-Fa, Lescar, Julien, Tam, James P.
Published 2021

Targeting the bacterial epitranscriptome for antibiotic development : discovery of novel tRNA-(N1G37) methyltransferase (TrmD) inhibitors

by Zhong, Wenhe, Koay, Ann, Ngo, Anna, Li, Yan, Nah, Qianhui, Wong, Yee Hwa, Chionh, Yok Hian, Ng, Hui Qi, Koh-Stenta, Xiaoying, Poulsen, Anders, Foo, Klement, McBee, Megan, Choong, Meng Ling, El Sahili, Abbas, Kang, Congbao, Matter, Alex, Lescar, Julien, Hill, Jeffrey, Dedon, Peter
Published 2021

Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A(star)11:01

by Gu, Yue, Wong, Yee Hwa, Liew, Chong Wai, Chan, Conrad EZ, Murali, Tanusya M, Yap, Jiawei, Too, Chien Tei, Purushotorman, Kiren, Hamidinia, Maryam, El Sahili, Abbas, Goh, Angeline TH, Teo, Rachel ZC, Wood, Kathryn J, Hanson, Brendon J, Gascoigne, Nicholas RJ, Lescar, Julien, Vathsala, Anantharaman, MacAry, Paul A
Published 2021

Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01

by Gu, Yue, Wong, Yee Hwa, Liew, Chong Wai, Chan, Conrad E. Z., Murali, Tanusya M., Yap, Jiawei, Too, Chien Tei, Purushotorman, Kiren, Hamidinia, Maryam, El Sahili, Abbas, Goh, Angeline T. H., Teo, Rachel Z. C., Wood, Kathryn J., Hanson, Brendon J., Gascoigne, Nicholas R. J., Lescar, Julien, Vathsala, Anantharaman, MacAry, Paul A.
Published 2019

Engineering SARS-CoV-2 specific cocktail antibodies into a bispecific format improves neutralizing potency and breadth

by Ku, Zhiqiang, Xie, Xuping, Lin, Jianqing, Gao, Peng, Wu, Bin, El Sahili, Abbas, Su, Hang, Liu, Yang, Ye, Xiaohua, Tan, Eddie Yongjun, Li, Xin, Fan, Xuejun, Goh, Boon Chong, Xiong, Wei, Boyd, Hannah, Muruato, Antonio E., Deng, Hui, Xia, Hongjie, Zou, Jing, Kalveram, Birte K., Menachery, Vineet D., Zhang, Ningyan, Lescar, Julien, Shi, Pei-Yong, An, Zhiqiang
Published 2023