Structural and functional studies of peptide asparaginyl ligases

by Hu, Side
Published 2022

Vypal2: a versatile peptide ligase for precision tailoring of proteins

by Zhang, Dingpeng, Wang, Zhen, Hu, Side, Lescar, Julien, Tam, James P., Liu, Chuan-Fa
Published 2022

pH-controlled protein orthogonal ligation using asparaginyl peptide ligases

by Zhang, Dingpeng, Wang, Zhen, Hu, Side, Balamkundu, Seetharamsing, To, Janet, Zhang, Xiaohong, Lescar, Julien, Tam, James P., Liu, Chuan-Fa
Published 2022

Engineering protein theranostics using bio-orthogonal asparaginyl peptide ligases

by Wang, Zhen, Zhang, Dingpeng, Hemu, Xinya, Hu, Side, To, Janet, Zhang, Xiaohong, Lescar, Julien, Tam, James P., Liu, Chuan-Fa
Published 2021

Asparaginyl endopeptidase-mediated protein C-terminal hydrazinolysis for the synthesis of bioconjugates

by Zhang, Dingpeng, Wang, Zhen, Hu, Side, Chan, Ning-Yu, Liew, Heng Tai, Lescar, Julien, Tam, James P., Liu, Chuan-Fa
Published 2022

A cascade enzymatic reaction scheme for irreversible transpeptidative protein ligation

by Xia, Yiyin, Li, Fupeng, Zhang, Xiaohong, Balamkundu, Seetharamsing, Tang, Fan, Hu, Side, Lescar, Julien, Tam, James P., Liu, Chuan-Fa
Published 2023

Substrate-binding glycine residues are major determinants for hydrolase and ligase activity of plant legumains

by Hemu, Xinya, Chan, Ning-Yu, Liew, Heng Tai, Hu, Side, Zhang, Xiaohong, Serra, Aida, Lescar, Julien, Liu, Chuan-Fa, Tam, James P.
Published 2023

Nγ-hydroxyasparagine: a multifunctional unnatural amino acid that is a good P1 substrate of asparaginyl peptide ligases

by Xia, Yiyin, To, Janet, Chan, Ning-Yu, Hu, Side, Liew, Heng Tai, Balamkundu, Seetharamsing, Zhang, Xiaohong, Lescar, Julien, Bhattacharjya, Surajit, Tam, James P., Liu, Chuan-Fa
Published 2022

Turning an asparaginyl endopeptidase into a peptide ligase

by Hemu, Xinya, El Sahili, Abbas, Hu, Side, Zhang, Xiaohong, Serra, Aida, Goh, Boon Chong, Darwis, Dina Amallia, Chen, Ming Wei, Sze, Siu Kwan, Liu, Chuan-Fa, Lescar, Julien, Tam, James P.
Published 2021

Structural determinants for peptide-bond formation by asparaginyl ligases

by Hemu, Xinya, El Sahili, Abbas, Hu, Side, Wong, Kaho, Chen, Yu, Wong, Yee Hwa, Zhang, Xiaohong, Serra, Aida, Goh, Boon Chong, Darwis, Dina Amallia, Chen, Ming Wei, Sze, Siu Kwan, Liu, Chuan-Fa, Lescar, Julien, Tam, James P.
Published 2021