A cascade enzymatic reaction scheme for irreversible transpeptidative protein ligation

Enzymatic peptide ligation holds great promise in the study of protein functions and development of protein therapeutics. Owing to their high catalytic efficiency and a minimal tripeptide recognition motif, peptidyl asparaginyl ligases (PALs) are particularly useful tools for bioconjugation. However...

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Bibliographic Details
Main Authors: Xia, Yiyin, Li, Fupeng, Zhang, Xiaohong, Balamkundu, Seetharamsing, Tang, Fan, Hu, Side, Lescar, Julien, Tam, James P., Liu, Chuan-Fa
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2023
Subjects:
Online Access:https://hdl.handle.net/10356/169065
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Institution: Nanyang Technological University
Language: English