Structural and biochemical characterization of non-structural protein 3 from flavivirus

by Phoo, Wint Wint
Published 2018

Functional interplay among the flavivirus NS3 protease, helicase, and cofactors

by Li, Kuohan, Phoo, Wint Wint, Luo, Dahai
Published 2014

Crystal structure of unlinked NS2B-NS3 protease from Zika virus

by Zhang, Zhenzhen, Li, Yan, Loh, Ying Ru, Phoo, Wint Wint, Hung, Alvin W., Kang, CongBao, Luo, Dahai
Published 2017

Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors

by Phoo, Wint Wint, Zhang, Zhenzhen, Wirawan, Melissa, Chew, Edwin Jun Chen, Chew, Alvin Bing Liang, Kouretova, Jenny, Steinmetzer, Torsten, Luo, Dahai
Published 2019

Dynamic interactions of post cleaved NS2B cofactor and NS3 protease identified by integrative structural approaches

by Quek, Jun-Ping, Ser, Zheng, Chew, Alvin Bing Liang, Li, Xin, Wang, Lili, Sobota, Radoslaw M., Luo, Dahai, Phoo, Wint Wint
Published 2022

Crystal structures of full length DENV4 NS2B-NS3 reveal the dynamic interaction between NS2B and NS3

by Phoo, Wint Wint, El Sahili, Abbas, Zhang, ZhenZhen, Chen, Ming Wei, Liew, Chong Wai, Lescar, Julien, Vasudevan, Subhash G., Luo, Dahai
Published 2022

Structure of the NS2B-NS3 protease from Zika virus after self-cleavage

by Phoo, Wint Wint, Li, Yan, Zhang, Zhenzhen, Lee, Michelle Yueqi, Loh, Ying Ru, Tan, Yaw Bia, Ng, Elizabeth Yihui, Lescar, Julien, Kang, CongBao, Luo, Dahai
Published 2017

NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication

by Swarbrick, Crystall M. D., Basavannacharya, Chandrakala, Chan, Kitti W. K., Chan, Shu-Ann, Singh, Daljit, Wei, Na, Phoo, Wint Wint, Luo, Dahai, Lescar, Julien, Vasudevan, Subhash G.
Published 2018

Structural insights into the inhibition of Zika virus NS2B-NS3 protease by a small-molecule inhibitor

by Li, Yan, Zhang, Zhenzhen, Phoo, Wint Wint, Loh, Ying Ru, Li, Rong, Yang, Hai Yan, Jansson, Anna E., Hill, Jeffrey, Keller, Thomas H., Nacro, Kassoum, Luo, Dahai, Kang, CongBao
Published 2020

A crystal structure of the dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication

by Zhao, Yongqian, Soh, Tingjin Sherryl, Zheng, Jie, Chan, Kitti Wing Ki, Phoo, Wint Wint, Lee, Chin Chin, Tay, Moon Y. F., Swaminathan, Kunchithapadam, Cornvik, Tobias Carl, Lim, Siew Pheng, Shi, Pei-Yong, Lescar, Julien, Vasudevan, Subhash G., Luo, Dahai
Published 2015

iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer

by Park, Dong Shin, Kozaki, Tatsuya, Tiwari, Satish Kumar, Moreira, Marco, Khalilnezhad, Ahad, Torta, Federico, Olivie, Nicolas, Thiam, Chung Hwee, Liani, Oniko, Silvin, Aymeric, Phoo, Wint Wint, Gao, Liang, Triebl, Alexander, Tham, Wai Kin, Goncalves, Leticia, Kong, Wan Ting, Raman, Sethi, Zhang, Xiao Meng, Dunsmore, Garett, Dutertre, Charles Antoine, Lee, Salanne, Ong, Jia Min, Balachander, Akhila, Khalilnezhad, Shabnam, Lum, Josephine, Duan, Kaibo, Lim, Ze Ming, Tan, Leonard, Low, Ivy, Utami, Kagistia Hana, Yeo, Xin Yi, Di Tommaso, Sylvaine, Dupuy, Jean-William, Varga, Balazs, Karadottir, Ragnhildur Thora, Madathummal, Mufeeda Changaramvally, Bonne, Isabelle, Malleret, Benoit, Binte, Zainab Yasin, Da, Ngan Wei, Tan, Yingrou, Wong, Wei Jie, Zhang, Jinqiu, Chen, Jinmiao, Sobota, Radoslaw M, Howland, Shanshan W, Ng, Lai Guan, Saltel, Frederic, Castel, David, Grill, Jacques, Minard, Veronique, Albani, Salvatore, Chan, Jerry KY, Thion, Morgane Sonia, Jung, Sang Yong, Wenk, Markus R, Pouladi, Mahmoud A, Pasqualini, Claudia, Angeli, Veronique, Cexus, Olivier NF, Ginhoux, Florent
Published 2024