Effect of Ser392 Phosphorylation on the Structure and Dynamics of the Polybasic Domain of ADP Ribosylation Factor Nucleotide Site Opener Protein: A Molecular Simulation Study

by Srinivasaraghavan, Kannan, Nacro, Kassoum, Grüber, Gerhard, Verma, Chandra Shekhar
Published 2016

Small molecules targeting the inactive form of the Mnk1/2 kinases

by Kannan, Srinivasaraghavan, Pradhan, Mohan R., Cherian, Joseph, Joseph, Thomas L., Poh, Zhi Ying, Hai Yan, Yang, Melvyn, Ho, Boping, Liu, Jeffrey, Hill, Nacro, Kassoum, Verma, Chandra Shekhar
Published 2021

Structural insights into the inhibition of Zika virus NS2B-NS3 protease by a small-molecule inhibitor

by Li, Yan, Zhang, Zhenzhen, Phoo, Wint Wint, Loh, Ying Ru, Li, Rong, Yang, Hai Yan, Jansson, Anna E., Hill, Jeffrey, Keller, Thomas H., Nacro, Kassoum, Luo, Dahai, Kang, CongBao
Published 2020

Probing the Binding Mechanism of Mnk Inhibitors by Docking and Molecular Dynamics Simulations

by Kannan, Srinivasaraghavan, Poulsen, Anders, Yang, Hai Yan, Ho, Melvyn, Ang, Shi Hua, Eldwin, Tan Sum Wai, Jeyaraj, Duraiswamy Athisayamani, Chennamaneni, Lohitha Rao, Liu, Boping, Hill, Jeffrey, Verma, Chandra Shekhar, Nacro, Kassoum
Published 2016

Probing the binding mechanism of Mnk inhibitors by docking and molecular dynamics simulations

by Kannan, Srinivasaraghavan, Poulsen, Anders, Yang, Haiyan, Ho, Melvyn, Ang, Shihua, Eldwin, Tan Sum Wai Wai, Jeyaraj, Duraiswamy Athisayamani Thisayamani, Chennamaneni, Lohitha Rao Ao, Liu, Boping, Hill, Jeffrey, Verma, Chandra, Nacro, Kassoum
Published 2016

MNK1 and MNK2 enforce expression of E2F1, FOXM1, and WEE1 to drive soft tissue sarcoma

by Ke, Xin-Yu, Chen, Ye, Tham, Valarie Yu-Yan, Lin, Ruby Yu-Tong, Dakle, Pushkar, Nacro, Kassoum, Puhaindran, Mark Edward, Houghton, Peter, Pang, Angela, Lee, Victor Kwanmin, Ding, Ling-Wen, Gery, Sigal, Hill, Jeffrey, Chen, Leilei, Xu, Liang, Koeffler, H Phillip
Published 2021

Topography of transcriptionally active chromatin in glioblastoma

by Xu, Liang, Chen, Ye, Huang, Yulun, Sandanaraj, Edwin, Yu, John S., Lin, Ruby Yu-Tong, Dakle, Pushkar, Ke, Xin-Yu, Chong, Yuk Kien, Koh, Lynnette, Mayakonda, Anand, Nacro, Kassoum, Hill, Jeffrey, Huang, Mo-Li, Gery, Sigal, Lim, See Wee, Huang, Zhengyun, Xu, Ying, Chen, Jianxiang, Bai, Longchuan, Wang, Shaomeng, Wakimoto, Hiroaki, Yeo, Tseng Tsai, Ang, Beng Ti, Müschen, Markus, Tang, Carol, Tan, Tuan Zea, Koeffler, H. Phillip
Published 2021

Optimization of selective mitogen-activated protein kinase interacting kinases 1 and 2 inhibitors for the treatment of blast crisis leukemia

by Yang, Haiyan, Chennamaneni, Lohitha Rao, Ho, Melvyn Wai Tuck, Ang, Shi Hua, Tan, Eldwin Sum Wai, Jeyaraj, Duraiswamy Athisayamani, Yeap, Yoon Sheng, Liu, Boping, Ong, Esther H. Q., Joy, Joma Kanikadu, Wee, John Liang Kuan, Kwek, Perlyn, Retna, Priya, Dinie, Nurul, Nguyen, Thuy Thi Hanh, Tai, Shi Jing, Manoharan, Vithya, Pendharkar, Vishal, Low, Choon Bing, Chew, Yun Shan, Vuddagiri, Susmitha, Sangthongpitag, Kanda, Choong, Meng Ling, Lee, May Ann, Kannan, Srinivasaraghavan, Verma, Chandra Shekhar, Poulsen, Anders, Lim, Sharon, Chuah, Charles Thuan Heng, Ong, Tiong Sin, Hill, Jeffrey, Matter, Alex, Nacro, Kassoum
Published 2020