Effect of Ser392 Phosphorylation on the Structure and Dynamics of the Polybasic Domain of ADP Ribosylation Factor Nucleotide Site Opener Protein: A Molecular Simulation Study

• المؤلفون الرئيسيون: Srinivasaraghavan, Kannan, Nacro, Kassoum, Grüber, Gerhard, Verma, Chandra Shekhar
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2016
• الموضوعات: Conformational samplings; Adp-ribosylation factors
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/82008; http://hdl.handle.net/10220/41058
• المؤسسة: Nanyang Technological University

ADP ribosylation factor nucleotide site opener (ARNO) as a guanine nucleotide exchange factor (GEF) activates small GTPases called ADP ribosylation factors (Arfs), which function as molecular switches and regulate a variety of cell biological events. ARNO directly interacts with the transmembrane a2...