Effect of Ser392 Phosphorylation on the Structure and Dynamics of the Polybasic Domain of ADP Ribosylation Factor Nucleotide Site Opener Protein: A Molecular Simulation Study

Effect of Ser392 Phosphorylation on the Structure and Dynamics of the Polybasic Domain of ADP Ribosylation Factor Nucleotide Site Opener Protein: A Molecular Simulation Study

ADP ribosylation factor nucleotide site opener (ARNO) as a guanine nucleotide exchange factor (GEF) activates small GTPases called ADP ribosylation factors (Arfs), which function as molecular switches and regulate a variety of cell biological events. ARNO directly interacts with the transmembrane a2...

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Bibliographic Details
Main Authors: Srinivasaraghavan, Kannan, Nacro, Kassoum, Grüber, Gerhard, Verma, Chandra Shekhar
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2016
Subjects:
Conformational samplings
Adp-ribosylation factors
Online Access:https://hdl.handle.net/10356/82008
http://hdl.handle.net/10220/41058
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/82008
http://hdl.handle.net/10220/41058

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