Effect of Ser392 Phosphorylation on the Structure and Dynamics of the Polybasic Domain of ADP Ribosylation Factor Nucleotide Site Opener Protein: A Molecular Simulation Study

• Main Authors: Srinivasaraghavan, Kannan, Nacro, Kassoum, Grüber, Gerhard, Verma, Chandra Shekhar
• 其他作者: School of Biological Sciences
• 格式: Article
• 語言: English
• 出版: 2016
• 主題: Conformational samplings; Adp-ribosylation factors
• 在線閱讀: https://hdl.handle.net/10356/82008; http://hdl.handle.net/10220/41058

ADP ribosylation factor nucleotide site opener (ARNO) as a guanine nucleotide exchange factor (GEF) activates small GTPases called ADP ribosylation factors (Arfs), which function as molecular switches and regulate a variety of cell biological events. ARNO directly interacts with the transmembrane a2...