Selinexor, a selective inhibitor of nuclear export, enhances the anti-tumor activity of olaparib in triple negative breast cancer regardless of BRCA1 mutation status

by Marijon, Hélène, Gery, Sigal, Chang, Hua, Landesman, Yosef, Shacham, Sharon, Lee, Dhong Hyun, de Gramont, Aimery, Koeffler, Harold Phillip
Published 2022

MNK1 and MNK2 enforce expression of E2F1, FOXM1, and WEE1 to drive soft tissue sarcoma

by Ke, Xin-Yu, Chen, Ye, Tham, Valarie Yu-Yan, Lin, Ruby Yu-Tong, Dakle, Pushkar, Nacro, Kassoum, Puhaindran, Mark Edward, Houghton, Peter, Pang, Angela, Lee, Victor Kwanmin, Ding, Ling-Wen, Gery, Sigal, Hill, Jeffrey, Chen, Leilei, Xu, Liang, Koeffler, H Phillip
Published 2021

Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma

by CHEN YE, Xu, Liang, Anand Mayakonda Thippeswamy, Huang, Mo-Li, Kanojia, Deepika, Tan, Tuan Zea, DAKLE PUSHKAR PRAVIN, LIN YU-TONG, RUBY, Ke, Xin-Yu, Said, Jonathan W, Chen, Jianxiang, Gery, Sigal, Ding, L.-W., Jiang, Yan-Yi, Pang, Angela, MARK EDWARD PUHAINDRAN, Boon Cher Goh, Koeffler, H Phillip
Published 2021

Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer

by Li, Li-Yan, Yang, Qian, Jiang, Yan-Yi, Yang, Wei, Jiang, Yuan, Li, Xiang, Hazawa, Masaharu, Zhou, Bo, Huang, Guo-Wei, Xu, Xiu-E, Gery, Sigal, Zhang, Ying, Ding, Ling-Wen, Ho, Allen S., Zumsteg, Zachary S., Wang, Ming-Rong, Fullwood, Melissa J., Freedland, Stephen J., Meltzer, Stephen J., Xu, Li-Yan, Li, En-Min, Koeffler, H. Phillip, Lin, De-Chen
Published 2022

Topography of transcriptionally active chromatin in glioblastoma

by Xu, Liang, Chen, Ye, Huang, Yulun, Sandanaraj, Edwin, Yu, John S., Lin, Ruby Yu-Tong, Dakle, Pushkar, Ke, Xin-Yu, Chong, Yuk Kien, Koh, Lynnette, Mayakonda, Anand, Nacro, Kassoum, Hill, Jeffrey, Huang, Mo-Li, Gery, Sigal, Lim, See Wee, Huang, Zhengyun, Xu, Ying, Chen, Jianxiang, Bai, Longchuan, Wang, Shaomeng, Wakimoto, Hiroaki, Yeo, Tseng Tsai, Ang, Beng Ti, Müschen, Markus, Tang, Carol, Tan, Tuan Zea, Koeffler, H. Phillip
Published 2021