Chromatin interaction neural network (ChINN): a machine learning-based method for predicting chromatin interactions from DNA sequences

by Cao, Fan, Zhang, Yu, Cai, Yichao, Animesh, Sambhavi, Zhang, Ying, Akincilar, Semih Can, Loh, Yan Ping, Li, Xinya, Chng, Wee Joo, Tergaonkar, Vinay, Kwoh, Chee Keong, Fullwood, Melissa J
Published 2021

Defining Essential Enhancers for Pluripotent Stem Cells Using a Features-Oriented CRISPR-Cas9 Screen

by Wang, H.F., Warrier, T., Farran, C.A., Zheng, Z.H., Xing, Q.R., Fullwood, Melissa J., Zhang, L.-F., Li, H., Xu, J., Lim, Tit-Meng, Loh, Y.-H.
Published 2021

The enhancer RNA ARIEL activates the oncogenic transcriptional program in T-cell acute lymphoblastic leukemia.

by Tan, Shi Hao, Leong, Wei Zhong, Ngoc, Phuong Cao Thi, Tan, Tze King, Bertulfo, Fatima Carla, Lim, Mei Chee, An, Omer, Li, Zhenhua, Yeoh, Allen Eng Juh, Fullwood, Melissa J, Tenen, Daniel G, Sanda, Takaomi
Published 2019

Super-Enhancers and Broad H3K4me3 Domains Form Complex Gene Regulatory Circuits Involving Chromatin Interactions

by Cao, Fan, Fang, Yiwen, Tan, Hong Kee, Goh, Yufen, Choy, Jocelyn Yeen Hui, Koh, Bryan Thean Howe, Tan, Jiong Hao, Bertin, Nicolas, Ramadass, Aroul, Hunter, Ewan, Green, Jayne, Salter, Matthew, Akoulitchev, Alexandre, Wang, Wilson, Chng, Wee Joo, Tenen, Daniel G, Fullwood, Melissa J
Published 2019

Aberrant hyperediting of the myeloma transcriptome by ADAR1 confers oncogenicity and is a marker of poor prognosis

by Teoh, Phaik Ju, An, Omer, Chung, Tae-Hoon, Chooi, Jing Yuan, Toh, Sabrina HM, Fan, Shuangyi, Wang, Wilson, Koh, Bryan TH, Fullwood, Melissa J, Ooi, Melissa G, de Mel, Sanjay, Soekojo, Cinnie Y, Chen, Leilei, Ng, Siok Bian, Yang, Henry, Chng, Wee Joo
Published 2019

Super Enhancer-Mediated Upregulation of HJURP Promotes Growth and Survival of t(4;14)-Positive

by Jia, Yunlu, Zhou, Jianbiao, Tan, Tze King, Chung, Tae-Hoon, Chen, Yongxia, Chooi, Jing-Yuan, Sanda, Takaomi, Fullwood, Melissa J, Xiong, Sinan, Toh, Sabrina HM, Balan, Kalpnaa, Wong, Regina WJ, Lim, Julia SL, Zhang, Enfan, Cai, Zhen, Shen, Peng, Chng, Wee Joo
Published 2023

Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer

by Li, Li-Yan, Yang, Qian, Jiang, Yan-Yi, Yang, Wei, Jiang, Yuan, Li, Xiang, Hazawa, Masaharu, Zhou, Bo, Huang, Guo-Wei, Xu, Xiu-E, Gery, Sigal, Zhang, Ying, Ding, Ling-Wen, Ho, Allen S., Zumsteg, Zachary S., Wang, Ming-Rong, Fullwood, Melissa J., Freedland, Stephen J., Meltzer, Stephen J., Xu, Li-Yan, Li, En-Min, Koeffler, H. Phillip, Lin, De-Chen
Published 2022

Pan-cancer pervasive upregulation of 3 ` UTR splicing drives tumourigenesis

by Chan, Jia Jia, Zhang, Bin, Chew, Xiao Hong, Salhi, Adil, Kwok, Zhi Hao, Lim, Chun You, Desi, Ng, Subramaniam, Nagavidya, Siemens, Angela, Kinanti, Tyas, Ong, Shane, Sanchez-Mejias, Avencia, Ly, Phuong Thao, An, Omer, Sundar, Raghav, Fan, Xiaonan, Wang, Shi, Siew, Bei En, Lee, Kuok Chung, Chong, Choon Seng, Lieske, Bettina, Cheong, Wai-Kit, Goh, Yufen, Fam, Wee Nih, Ooi, Melissa G., Koh, Bryan T. H., Iyer, Shridhar Ganpathi, Ling, Wen Huan, Chen, Jianbin, Yoong, Boon-Koon, Chanwat, Rawisak, Bonney, Glenn Kunnath, Goh, Brian K. P., Zhai, Weiwei, Fullwood, Melissa J., Wang, Wilson, Tan, Ker-Kan, Chng, Wee Joo, Dan, Yock Young, Pitt, Jason J., Roca, Xavier, Guccione, Ernesto, Vardy, Leah A., Chen, Leilei, Gao, Xin, Chow, Pierce K. H., Yang, Henry, Tay, Yvonne
Published 2022

Pan-cancer pervasive upregulation of 3 ' UTR splicing drives tumourigenesis

by Chan, Jia Jia, Zhang, Bin, Chew, Xiao Hong, Salhi, Adil, Kwok, Zhi Hao, Lim, Chun You, Desi, Ng, Subramaniam, Nagavidya, Siemens, Angela, Kinanti, Tyas, Ong, Shane, Sanchez-Mejias, Avencia, Ly, Phuong Thao, An, Omer, Sundar, Raghav, Fan, Xiaonan, Wang, Shi, Siew, Bei En, Lee, Kuok Chung, Chong, Choon Seng, Lieske, Bettina, Cheong, Wai-Kit, Goh, Yufen, Fam, Wee Nih, Ooi, Melissa G, Koh, Bryan TH, Iyer, Shridhar Ganpathi, Ling, Wen Huan, Chen, Jianbin, Yoong, Boon-Koon, Chanwat, Rawisak, Bonney, Glenn Kunnath, Goh, Brian KP, Zhai, Weiwei, Fullwood, Melissa J, Wang, Wilson, Tan, Ker-Kan, Chng, Wee Joo, Dan, Yock Young, Pitt, Jason J, Roca, Xavier, Guccione, Ernesto, Vardy, Leah A, Chen, Leilei, Gao, Xin, Chow, Pierce KH, Yang, Henry, Tay, Yvonne
Published 2022