Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors

Structures of Zika virus NS2B-NS3 protease in complex with peptidomimetic inhibitors

Zika virus NS2B-NS3 protease plays an essential role in viral replication by processing the viral polyprotein into individual proteins. The viral protease is therefore considered as an ideal antiviral drug target. To facilitate the development of protease inhibitors, we report three high-resolution...

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Bibliographic Details
Main Authors: Phoo, Wint Wint, Zhang, Zhenzhen, Wirawan, Melissa, Chew, Edwin Jun Chen, Chew, Alvin Bing Liang, Kouretova, Jenny, Steinmetzer, Torsten, Luo, Dahai
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2019
Subjects:
Science::Medicine
NS3 Protease
Zika Virus
Online Access:https://hdl.handle.net/10356/80153
http://hdl.handle.net/10220/50366
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/80153
http://hdl.handle.net/10220/50366

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