The flavivirus NS2B–NS3 protease–helicase as a target for antiviral drug development

The flavivirus NS3 protein is associated with the endoplasmic reticulum membrane via its close interaction with the central hydrophilic region of the NS2B integral membrane protein. The multiple roles played by the NS2B–NS3 protein in the virus life cycle makes it an attractive target for antiviral...

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Bibliographic Details
Main Authors: Luo, Dahai, Vasudevan, Subhash, Lescar, Julien
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/10356/81793
http://hdl.handle.net/10220/40998
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Institution: Nanyang Technological University
Language: English