Dynamic interactions of post cleaved NS2B cofactor and NS3 protease identified by integrative structural approaches

Dynamic interactions of post cleaved NS2B cofactor and NS3 protease identified by integrative structural approaches

Diseases caused by flaviviruses such as dengue virus (DENV) and West Nile Virus (WNV), are a serious threat to public health. The flavivirus single-stranded RNA genome is translated into a polyprotein which is cleaved into three structural proteins and seven non-structural proteins by the viral and...

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Bibliographic Details
Main Authors: Quek, Jun-Ping, Ser, Zheng, Chew, Alvin Bing Liang, Li, Xin, Wang, Lili, Sobota, Radoslaw M., Luo, Dahai, Phoo, Wint Wint
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2022
Subjects:
Science::Medicine
NS2B-NS3 Protease
Dengue Virus
Online Access:https://hdl.handle.net/10356/163157
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/163157

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