Going native: Complete removal of protein purification affinity tags by simple modification of existing tags and proteases

by Goh, Hui Chin, Sobota, Radoslaw M., Ghadessy, Farid J., Nirantar, Saurabh
Published 2017

CD137 ligand interacts with CD32a to trigger reverse CD137 ligand signaling

by Zeng, Qun, Soe, Ye Mon, Lim, Yanting, Sobota, Radoslaw M, Schwarz, Herbert
Published 2023

KOPI: kinase inhibitor proteome impact analysis

by Li, Ginny Xiaohe, Zhao, Tianyun, Wang, Loo Chien, Choi, Hyungwon, Lim, Yan Ting, Sobota, Radoslaw M.
Published 2023

Modulation of protein-interaction states through the cell cycle

by Dai, Lingyun, Zhao, Tianyun, Bisteau, Xavier, Sun, Wendi, Prabhu, Nayana, Lim, Yan Ting, Sobota, Radoslaw M., Kaldis, Philipp, Nordlund, Pär
Published 2019

Dynamic interactions of post cleaved NS2B cofactor and NS3 protease identified by integrative structural approaches

by Quek, Jun-Ping, Ser, Zheng, Chew, Alvin Bing Liang, Li, Xin, Wang, Lili, Sobota, Radoslaw M., Luo, Dahai, Phoo, Wint Wint
Published 2022

A diecast mineralization process forms the tough mantis shrimp dactyl club

by Amini, Shahrouz, Tadayon, Maryam, Loke, Jun Jie, Kumar, Akshita, Kanagavel, Deepankumar, Le Ferrand, Hortense, Duchamp, Martial, Raida, Manfred, Sobota, Radoslaw M., Chen, Liyan, Hoon, Shawn, Miserez, Ali
Published 2021

Complete sequences of the velvet worm slime proteins reveal that slime formation is enabled by disulfide bonds and intrinsically disordered regions

by Lu, Yang, Sharma, Bhargy, Soon, Wei Long, Shi, Xiangyan, Zhao, Tianyun, Lim, Yan Ting, Sobota, Radoslaw M., Hoon, Shawn, Pilloni, Giovanni, Usadi, Adam, Pervushin, Konstantin, Miserez, Ali
Published 2023

Hybrid structural modeling of alloantibody binding to human leukocyte antigen with rapid and reproducible cross-linking mass spectrometry

by Ser, Zheng, Gu, Yue, Yap, Jiawei, Lim, Yan Ting, Wang, Shi Mei, Hamidinia, Maryam, Murali, Tanusya Murali, Kumar, Ragini, Gascoigne, Nicholas RJ, Macary, Paul A, Sobota, Radoslaw M
Published 2024

Cellular thermal shift assay for the identification of drug-target interactions in the Plasmodium falciparum proteome

by Dziekan, Jerzy Michal, Wirjanata, Grennady, Dai, Lingyun, Go, Ka Diam, Yu, Han, Lim, Yan Ting, Chen, Liyan, Wang, Loo Chien, Puspita, Brenda, Prabhu, Nayana, Sobota, Radoslaw M., Nordlund, Pär, Bozdech, Zbynek
Published 2022

Monitoring structural modulation of redox-sensitive proteins in cells with MS-CETSA

by Sun, Wendi, Dai, Lingyun, Yu, Han, Puspita, Brenda, Zhao, Tianyun, Li, Feng, Tan, Justin L., Lim, Yan Ting, Chen, Ming Wei, Sobota, Radoslaw M., Tenen, Daniel G., Prabhu, Nayana, Nordlund, Pär
Published 2019

Unveiling the influence of tumor microenvironment and spatial heterogeneity on temozolomide resistance in glioblastoma using an advanced human in vitro model of the blood-brain bar...

by Lam, Maxine S. Y., Aw, Joey J. Y., Tan, Damien, Vijayakumar, Ragavi, Lim, Grace Hui Yi, Yada, Swathi, Pang, Qing You, Barker, Nick, Tang, Carol, Ang, Beng Ti, Sobota, Radoslaw M., Pavesi, Andrea
Published 2024

Bioinspired short peptide hydrogel for versatile encapsulation and controlled release of growth factor therapeutics

by Hiew, Shu Hui, Wang, Jun Kit, Koh, Kenrick, Yang, Haibo, Bacha, Abbas, Lin, Junquan, Yip, Yun Sheng, Vos, Marcus Ivan Gerard, Chen, Liyan, Sobota, Radoslaw M., Tan, Nguan Soon, Tay, Chor Yong, Miserez, Ali
Published 2022

Thermal proximity coaggregation for system-wide profiling of protein complex dynamics in cells

by Tan, Chris Soon Heng, Go, Ka Diam, Bisteau, Xavier, Dai, Lingyun, Yong, Chern Han, Prabhu, Nayana, Ozturk, Mert Burak, Lim, Yan Ting, Sreekumar, Lekshmy, Lengqvist, Johan, Tergaonkar, Vinay, Kaldis, Philipp, Sobota, Radoslaw M., Nordlund, Pär
Published 2019

Biomineralization of mantis shrimp dactyl club following molting: apatite formation and brominated organic components

by Chua, Isaiah Jia Qing, Christensen, Thorbjørn Erik Køppen, Palle, Jonas, Wittig, Nina Kølln, Grünewald, Tilman A., Garrevoet, Jan, Spiers, Kathryn M., Castillo-Michel, Hiram, Schramm, Andreas, Chien, Wang Loo, Sobota, Radoslaw M., Birkedal, Henrik, Miserez, Ali
Published 2024

Unbiased profiling of isogenic huntington disease hPSC-derived CNS and peripheral cells reveals strong cell-type specificity of CAG length effects

by Ziaei, Amin, Zeng, Ruizhu, Low, Donovan, Aminkeng, Folefac, Sobota, Radoslaw M., Ginhoux, Florent, Petretto, Enrico, Pouladi, Mahmoud A., Langley, Sarah Raye, Ooi, Jolene, Xu, Xiaohong, Utami, Kagistia H., Sim, Bernice, Huang, Yihui, Harmston, Nathan P., Tay, Yi Lin
Published 2019

An efficient proteome-wide strategy for discovery and characterization of cellular nucleotide-protein interactions

by Lim, Yan Ting, Prabhu, Nayana, Dai, Lingyun, Go, Ka Diam, Chen, Dan, Sreekumar, Lekshmy, Egeblad, Louise, Eriksson, Staffan, Chen, Liyan, Veerappan, Saranya, Teo, Hsiang Ling, Tan, Chris Soon Heng, Lengqvist, Johan, Larsson, Andreas, Sobota, Radoslaw M., Nordlund, Pär
Published 2019

Squid suckerin-spider silk fusion protein hydrogel for delivery of mesenchymal stem cell secretome to chronic wounds

by Koh, Kenrick, Wang, Jun Kit, Chen, James Xiao Yuan, Hiew, Shu Hui, Cheng, Hong Sheng, Gabryelczyk, Bartosz, Vos, Marcus Ivan Gerard, Yip, Yun Sheng, Chen, Liyan, Sobota, Radoslaw M., Chua, Damian Kang Keat, Tan, Nguan Soon, Tay, Chor Yong, Miserez, Ali
Published 2023

CAMK2D serves as a molecular scaffold for RNF8-MAD2 complex to induce mitotic checkpoint in glioma

by Chuah, You Heng, Tay, Emmy Xue Yun, Grinchuk, Oleg V., Yoon, Jeehyun, Feng, Jia, Kannan, Srinivasaraghavan, Robert, Matius, Jakhar, Rekha, Liang, Yajing, Lee, Bernice Woon Li, Wang, Loo Chien, Lim, Yan Ting, Zhao, Tianyun, Sobota, Radoslaw M., Lu, Guang, Low, Boon Chuan, Crasta, Karen Carmelina, Verma, Chandra Shekhar, Lin, Zhewang, Ong, Derrick Sek Tong
Published 2024

Dependency of NELF-E-SLUG-KAT2B epigenetic axis in breast cancer carcinogenesis

by Zhang, Jieqiong, Hu, Zhenhua, Chung, Hwa Hwa, Tian, Yun, Lau, Kah Weng, Ser, Zheng, Lim, Yan Ting, Sobota, Radoslaw M., Leong, Hwei Fen, Chen, Benjamin Jieming, Yeo, Clarisse Jingyi, Tan, Shawn Ying Xuan, Kang, Jian, Tan, Dennis Eng Kiat, Sou, Ieng Fong, McClurg, Urszula Lucja, Lakshmanan, Manikandan, Vaiyapuri, Thamil Selvan, Raju, Anandhkumar, Wong, Esther Sook Miin, Tergaonkar, Vinay, Rajarethinam, Ravisankar, Pathak, Elina, Tam, Wai Leong, Tan, Ern Yu, Tee, Wee-Wei
Published 2023

Domain-specific p53 mutants activate EGFR by distinct mechanisms exposing tissue-independent therapeutic vulnerabilities

by Ho, Teresa Lai Fong, Lee, May Yin, Goh, Hui Chin, Ng, Germaine Yi Ning, Lee, Jane Jia Hui, Kannan, Srinivasaraghavan, Lim, Yan Ting, Zhao, Tianyun, Lim, Edwin Kok Hao, Phua, Cheryl Zi Jin, Lee, Yi Fei, Lim, Rebecca Yi Xuan, Ng, Perry Jun Hao, Yuan, Ju, Chan, Dedrick Kok Hong, Lieske, Bettina, Chong, Choon Seng, Lee, Kuok Chung, Lum, Jeffrey, Cheong, Wai Kit, Yeoh, Khay Guan, Tan, Ker Kan, Sobota, Radoslaw M, Verma, Chandra S, Lane, David P, Tam, Wai Leong, Venkitaraman, Ashok R
Published 2023