Monitoring structural modulation of redox-sensitive proteins in cells with MS-CETSA

• المؤلفون الرئيسيون: Sun, Wendi, Dai, Lingyun, Yu, Han, Puspita, Brenda, Zhao, Tianyun, Li, Feng, Tan, Justin L., Lim, Yan Ting, Chen, Ming Wei, Sobota, Radoslaw M., Tenen, Daniel G., Prabhu, Nayana, Nordlund, Pär
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2019
• الموضوعات: DRNTU::Science::Biological sciences; Reactive Oxygen Species; Cellular Thermal Shift Assay
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/95947; http://hdl.handle.net/10220/49460
• المؤسسة: Nanyang Technological University

Reactive oxygen species (ROS) induce different cellular stress responses but can also mediate cellular signaling. Augmented levels of ROS are associated with aging, cancer as well as various metabolic and neurological disorders. ROS can also affect the efficacy and adverse effects of drugs. Although...