The cellular thermal shift assay : a novel biophysical assay for in situ drug target engagement and mechanistic biomarker studies

by Martinez Molina, Daniel, Nordlund, Pär
Published 2018

High-resolution insights into binding of unfolded polypeptides by the PPIase chaperone SlpA

by Löw, Christian, Nordlund, Pär, Quistgaard, Esben M.
Published 2013

Optimisation of over-expression in E. coli and biophysical characterisation of human membrane protein synaptogyrin 1

by Löw, Christian, Jegerschöld, Caroline, Kovermann, Michael, Moberg, Per, Nordlund, Pär
Published 2013

Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states

by Chen, Dan, Jansson, Anna, Sim, Daniel, Larsson, Andreas, Nordlund, Pär
Published 2018

Structural basis for PTPA interaction with the invariant C-terminal tail of PP2A

by Löw, Christian, Quistgaard, Esben M., Kovermann, Michael, Anandapadamanaban, Madhanagopal, Balbach, Jochen, Nordlund, Pär
Published 2015

Structure of the Open Reading Frame 49 Protein Encoded by Kaposi Sarcoma-Associated Herpesvirus

by Hew, Kelly, Veerappan, Saranya, Sim, Daniel, Cornvik, Tobias, Nordlund, Pär, Dahlroth, Sue-Li
Published 2017

Structural and biochemical characterization of Human PR70 in isolation and in complex with the scaffolding subunit of protein phosphatase 2A

by Dovega, Rebecca, Tsutakawa, Susan, Quistgaard, Esben M., Anandapadamanaban, Madhanagopal, Löw, Christian, Nordlund, Pär
Published 2014

Structural and biophysical characterization of the cytoplasmic domains of human BAP29 and BAP31

by Löw, Christian, Moberg, Per, Guettou, Fatma, Maddi, Karthik, Nordlund, Pär, Quistgaard, Esben M.
Published 2013

Structure of the Varicella Zoster Virus Thymidylate Synthase Establishes Functional and Structural Similarities as the Human Enzyme and Potentiates Itself as a Target of Brivudine

by Hew, Kelly, Dahlroth, Sue-Li, Veerappan, Saranya, Pan, Lucy Xin, Cornvik, Tobias, Nordlund, Pär
Published 2016

Structure of the C-terminal domain of the multifunctional ICP27 protein from herpes simplex virus 1

by Nordlund, Par, Patel, Vidhi, Dahlroth, Sue-Li, Rajakannan, Venkatachalam, Ho, Hai Ting, Cornvik, Tobias
Published 2015

Engineering protein thermostability using a generic activity-independent biophysical screen inside the cell

by Asial, Ignacio, Cheng, Yue Xiang, Engman, Henrik, Dollhopf, Maria, Wu, Binghuang, Nordlund, Pär, Cornvik, Tobias
Published 2014

Molecular insights into substrate recognition and catalytic mechanism of the chaperone and FKBP peptidyl-prolyl isomerase SlyD

by Quistgaard, Esben M., Weininger, Ulrich, Ural-Blimke, Yonca, Modig, Kristofer, Nordlund, Pär, Akke, Mikael, Löw, Christian
Published 2016

Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism

by Egeblad, Louise, Welin, Martin, Flodin, Susanne, Gräslund, Susanne, Wang, Liya, Balzarini, Jan, Eriksson, Staffan, Nordlund, Pär
Published 2013

Interaction between human BAP31 and respiratory syncytial virus small hydrophobic (SH) protein

by Li, Yan, Jain, Neeraj, Limpanawat, Suweeraya, To, Janet, Quistgaard, Esben M., Nordlund, Par, Thanabalu, Thirumaran, Torres, Jaume
Published 2015

The crystal structure of the DNA-binding domain of vIRF-1 from the oncogenic KSHV reveals a conserved fold for DNA binding and reinforces its role as a transcription factor

by Hew, Kelly, Dahlroth, Sue-Li, Venkatachalam, Rajakannan, Nasertorabi, Fariborz, Lim, Bee Ting, Cornvik, Tobias Carl, Nordlund, Pär
Published 2013

Modulation of protein-interaction states through the cell cycle

by Dai, Lingyun, Zhao, Tianyun, Bisteau, Xavier, Sun, Wendi, Prabhu, Nayana, Lim, Yan Ting, Sobota, Radoslaw M., Kaldis, Philipp, Nordlund, Pär
Published 2019

Structural insights into substrate recognition in proton-dependent oligopeptide transporters

by Quistgaard, Esben M., Jong, Agnes Jin Oi, Nordlund, Pär, Löw, Christian, Guettou, Fatma, Trésaugues, Lionel, Moberg, Per, Jegerschöld, Caroline, Zhu, Lin
Published 2013

Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay

by Dziekan, Jerzy Michal, Yu, Han, Chen, Dan, Dai, Lingyun, Wirjanata, Grennady, Larsson, Andreas, Prabhu, Nayana, Sobota, Radoslaw Mikolaj, Bozdech, Zbynek, Nordlund, Pär
Published 2021

A synthetic polyphosphoinositide headgroup surrogate in complex with SHIP2 provides a rationale for drug discovery

by Persson, Camilla, Cozier, Gyles, Trésaugues, Lionel, Erneux, Christophe, Nordlund, Pär, Mills, Stephen J., Thomas, Mark P., Riley, Andrew M., Potter, Barry V. L.
Published 2013

Nanobody mediated crystallization of an archeal mechanosensitive channel

by Moberg, Per, Quistgaard, Esben M., Löw, Christian, Yau, Yin Hoe, Pardon, Els, Jegerschöld, Caroline, Wåhlin, Lisa, Geifman-Shochat, Susana, Steyaert, Jan, Nordlund, Pär
Published 2014