Structural analyses of human thymidylate synthase reveal a site that may control conformational switching between active and inactive states

by Chen, Dan, Jansson, Anna, Sim, Daniel, Larsson, Andreas, Nordlund, Pär
Published 2018

Predicting allosteric effects from orthosteric binding in Hsp90-ligand interactions : implications for fragment-based drug design

by Chandramohan, Arun, Krishnamurthy, Srinath, Larsson, Andreas, Nordlund, Paer, Jansson, Anna, Anand, Ganesh S.
Published 2018

Identifying purine nucleoside phosphorylase as the target of quinine using cellular thermal shift assay

by Dziekan, Jerzy Michal, Yu, Han, Chen, Dan, Dai, Lingyun, Wirjanata, Grennady, Larsson, Andreas, Prabhu, Nayana, Sobota, Radoslaw Mikolaj, Bozdech, Zbynek, Nordlund, Pär
Published 2021

CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil

by Almqvist, Helena, Axelsson, Hanna, Jafari, Rozbeh, Dan, Chen, Mateus, André, Haraldsson, Martin, Larsson, Andreas, Molina, Daniel Martinez, Artursson, Per, Lundbäck, Thomas, Nordlund, Pär
Published 2018

Proapoptotic cyclic peptide BC71 targets cell-surface GRP78 and functions as an anticancer therapeutic in mice

by Kao, Chieh, Chandna, Ritu, Ghode, Abhijeet, Dsouza, Charlotte, Chen, Mo, Larsson, Andreas, Lim, Siau Hoi, Wang, Minjun, Cao, Zhonglian, Zhu, Yizhun, Anand, Ganesh S., Ge, Ruowen
Published 2018

Modulating release of ranibizumab and aflibercept from thiolated chitosan-based hydrogels for potential treatment of ocular neovascularization

by Moreno, Miguel, Pow, Poh Yih, Tan, Su Teng Tabitha, Nirmal, Sonali, Larsson, Andreas, Radhakrishnan, Krishna, Nirmal, Jayabalan, Quah, Soo Tng, Shochat, Susana Geifman, Agrawal, Rupesh, Venkatraman, Subbu S.
Published 2017

Backbone resonance assignment for the N-terminal region of bacterial tRNA-(N1G37) methyltransferase

by Yan, Li, Zhong, Wenhe, Koay, Ann Zhufang, Ng, Hui Qi, Koh‑Stenta, Xiaoying, Nah, Qianhui, Lim, Siau Hoi, Larsson, Andreas, Lescar, Julien, Hill, Jeffrey, Dedon, Peter C., Kang, CongBao
Published 2021

An efficient proteome-wide strategy for discovery and characterization of cellular nucleotide-protein interactions

by Lim, Yan Ting, Prabhu, Nayana, Dai, Lingyun, Go, Ka Diam, Chen, Dan, Sreekumar, Lekshmy, Egeblad, Louise, Eriksson, Staffan, Chen, Liyan, Veerappan, Saranya, Teo, Hsiang Ling, Tan, Chris Soon Heng, Lengqvist, Johan, Larsson, Andreas, Sobota, Radoslaw M., Nordlund, Pär
Published 2019

Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality

by Dai, Lingyun, Prabhu, Nayana, Diam, Go Ka, Sobota, Radoslaw, Larsson, Andreas, Nordlund, Pär, McCormick, Frank, Ghosh, Sujoy, Epstein, David M., Dymock, Brian W., Lee, Sang Hyun, Kitagawa, Mayumi, Liao, Pei-Ju, Lee, Kyung Hee, Wong, Jasmine, Shang, See Cheng, Minami, Noriaki, Sampetrean, Oltea, Saya, Hideyuki
Published 2018