Optimisation of over-expression in E. coli and biophysical characterisation of human membrane protein synaptogyrin 1

Progress in functional and structural studies of integral membrane proteins (IMPs) is lacking behind their soluble counterparts due to the great challenge in producing stable and homogeneous IMPs. Low natural abundance, toxicity when over-expressed and potential lipid requirements of IMPs are only a...

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Bibliographic Details
Main Authors: Löw, Christian, Jegerschöld, Caroline, Kovermann, Michael, Moberg, Per, Nordlund, Pär
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2013
Subjects:
Online Access:https://hdl.handle.net/10356/95770
http://hdl.handle.net/10220/9349
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Institution: Nanyang Technological University
Language: English