Interaction between human BAP31 and respiratory syncytial virus small hydrophobic (SH) protein

• Main Authors: Li, Yan, Jain, Neeraj, Limpanawat, Suweeraya, To, Janet, Quistgaard, Esben M., Nordlund, Par, Thanabalu, Thirumaran, Torres, Jaume
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences::Human anatomy and physiology
• Online Access: https://hdl.handle.net/10356/99785; http://hdl.handle.net/10220/25675
• Institution: Nanyang Technological University

The small hydrophobic (SH) protein is a short channel-forming polypeptide encoded by the human respiratory syncytial virus (hRSV). Deletion of SH protein leads to the viral attenuation in mice and primates, and delayed apoptosis in infected cells. We have used a membrane-based yeast two-hybrid syste...