Bioinspired short peptide hydrogel for versatile encapsulation and controlled release of growth factor therapeutics

• Main Authors: Hiew, Shu Hui, Wang, Jun Kit, Koh, Kenrick, Yang, Haibo, Bacha, Abbas, Lin, Junquan, Yip, Yun Sheng, Vos, Marcus Ivan Gerard, Chen, Liyan, Sobota, Radoslaw M., Tan, Nguan Soon, Tay, Chor Yong, Miserez, Ali
• Other Authors: School of Materials Science and Engineering
• Format: Article
• Language: English
• Published: 2022
• Subjects: Engineering::Materials; Peptide Hydrogel; Supramolecular Self-Assembly
• Online Access: https://hdl.handle.net/10356/160212
• Institution: Nanyang Technological University

A short bioinspired octapeptide, GV8, can self-assemble under mild conditions into biodegradable supramolecular physical hydrogels with high storage modulus and good biocompatibility. GV8 hydrogels can encapsulate both single or multiple macromolecular protein-based therapeutics in a simple one-pot...