Themis-associated phosphatase activity controls signaling in T cell development

بواسطة Mehta, Monika, Brzostek, Joanna, Chen, Elijah W, Tung, Desmond WH, Chen, Shuting, Sankaran, Shvetha, Yap, Jiawei, Rybakin, Vasily, Gascoigne, Nicholas RJ
منشور في 2023

Lck bound to coreceptor is less active than free Lck

بواسطة Wei, Qianru, Brzostek, Joanna, Sankaran, Shvetha, Casas, Javier, Hew, Lois Shi-Qi, Yap, Jiawei, Zhao, Xiang, Wojciech, Lukasz, Gascoigne, Nicholas RJ
منشور في 2023

Targeting car to the peptide?mhc complex reveals distinct signaling compared to that of tcr in a jurkat t cell model

بواسطة Wu, Ling, Brzostek, Joanna, Sankaran, Shvetha, Wei, Qianru, Yap, Jiawei, Tan, Triscilla Y. Y., Lai, Junyun, Macary, Paul A., Gascoigne, Nicholas R. J.
منشور في 2022

Expansion of an Unusual Virtual Memory CD8+ Subpopulation Bearing V?3.2 TCR in Themis-Deficient Mice

بواسطة Prasad, Mukul, Wojciech, Lukasz, Brzostek, Joanna, Hu, Jianfang, Chua, Yen Leong, Tung, Desmond Wai Hon, Yap, Jiawei, Rybakin, Vasily, Gascoigne, Nicholas R. J.
منشور في 2022

Bioorthogonal cleavage and exchange of major histocompatibility complex ligands by employing azobenzene-containing peptides

بواسطة Choo, Joanna A. L., Thong, Sock Yue, Yap, Jiawei, van Esch, Wim J. E., Raida, Manfred, Meijers, Rob, Lescar, Julien, Verhelst, Steven H. L., Grotenbreg, Gijsbert M.
منشور في 2015

Hybrid structural modeling of alloantibody binding to human leukocyte antigen with rapid and reproducible cross-linking mass spectrometry

بواسطة Ser, Zheng, Gu, Yue, Yap, Jiawei, Lim, Yan Ting, Wang, Shi Mei, Hamidinia, Maryam, Murali, Tanusya Murali, Kumar, Ragini, Gascoigne, Nicholas RJ, Macary, Paul A, Sobota, Radoslaw M
منشور في 2024

Utilizing distinct CAR and TCR signaling to generate enhanced cellular immunotherapy

بواسطة Gascoigne, Nicholas RJ, Wu, Ling, Brzostek, Joanna, Wei, Qianru, Vale, Previtha Dawn Sakthi, Koh, Clara KT, Chua, Yen Long, Yap, Jiawei, Tan, Triscilla YY, Lai, Junyun, MacAry, Paul A
منشور في 2023

CD28-CAR-T cell activation through FYN kinase signaling rather than LCK enhances therapeutic performance

بواسطة Wu, Ling, Brzostek, Joanna, Vale, Previtha Dawn Sakthi, Wei, Qianru, Koh, Clara KT, Ong, June Xu Hui, Wu, Liang-zhe, Tan, Jia Chi, Chua, Yen Leong, Yap, Jiawei, Song, Yuan, Tan, Vivian Jia Yi, Tan, Triscilla YY, Lai, Junyun, MacAry, Paul A, Gascoigne, Nicholas RJ
منشور في 2023

Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A(star)11:01

بواسطة Gu, Yue, Wong, Yee Hwa, Liew, Chong Wai, Chan, Conrad EZ, Murali, Tanusya M, Yap, Jiawei, Too, Chien Tei, Purushotorman, Kiren, Hamidinia, Maryam, El Sahili, Abbas, Goh, Angeline TH, Teo, Rachel ZC, Wood, Kathryn J, Hanson, Brendon J, Gascoigne, Nicholas RJ, Lescar, Julien, Vathsala, Anantharaman, MacAry, Paul A
منشور في 2021

Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01

بواسطة Gu, Yue, Wong, Yee Hwa, Liew, Chong Wai, Chan, Conrad E. Z., Murali, Tanusya M., Yap, Jiawei, Too, Chien Tei, Purushotorman, Kiren, Hamidinia, Maryam, El Sahili, Abbas, Goh, Angeline T. H., Teo, Rachel Z. C., Wood, Kathryn J., Hanson, Brendon J., Gascoigne, Nicholas R. J., Lescar, Julien, Vathsala, Anantharaman, MacAry, Paul A.
منشور في 2019