Crystal structure and functional analysis of mycobacterial erythromycin resistance methyltransferase Erm38 reveals its RNA-binding site

by Goh, Boon Chong, Xiang, Xinyu, Lescar, Julien, Dedon, Peter C.
Published 2022

Thiazolidin-5-imine formation as a catalyst-free bioorthogonal reaction for protein and live cell labeling

by Bi, Xiaobao, Yin, Juan, Rao, Chang, Balamkundu, Seetharamsing, Banerjee, Biplab, Zhang, Dingpeng, Zhang, Dawei, Dedon, Peter C., Liu, Chuan-Fa
Published 2021

Tagging transferrin receptor with a disulfide FRET probe to gauge the redox state in endosomal compartments

by Bi, Xiaobao, Yin, Juan, Zhang, Dingpeng, Zhang, Xiaohong, Balamkundu, Seetharamsing, Lescar, Julien, Dedon, Peter C., Tam, James P., Liu, Chuan-Fa
Published 2021

Discovery of a new predominant cytosine DNA modification that is linked to gene expression in malaria parasites

by Hammam, Elie, Ananda, Guruprasad, Sinha, Ameya, Scheidig-Benatar, Christine, Bohec, Mylene, Preiser, Peter Rainer, Dedon, Peter C., Scherf, Artur, Vembar, Shruthi S.
Published 2020

tRNA epitranscriptomics and biased codon are linked to proteome expression in Plasmodium falciparum

by Dedon, Peter C., Preiser, Peter Rainer, Ng, Chee Sheng, Sinha, Ameya, Aniweh, Yaw, Nah, Qianhui, Babu, Indrakanti Ramesh, Gu, Chen, Chionh, Yok Hian
Published 2019

Three distinct 3-methylcytidine (m3C) methyltransferases modify tRNA and mRNA in mice and humans

by Xu, Luang, Liu, Xinyu, Sheng, Na, Oo, Kyaw Soe, Liang, Junxin, Chionh, Yok Hian, Xu, Juan, Ye, Fuzhou, Gao, Yong-Gui, Dedon, Peter C., Fu, Xin-Yuan
Published 2018

Malaria parasite stress tolerance is regulated by DNMT2-mediated tRNA cytosine methylation

by Hammam, Elie, Sinha, Ameya, Baumgarten, Sebastian, Nardella, Flore, Liang, Jiaqi, Miled, Samia, Bonhomme, Frédéric, Erdmann, Diane, Arcangioli, Benoit, Arimondo, Paola B., Dedon, Peter, Preiser, Peter, Scherf, Artur
Published 2023

An RNA modification enzyme directly senses reactive oxygen species for translational regulation in Enterococcus faecalis

by Lee, Wei Lin, Sinha, Ameya, Lam, Ling Ning, Loo, Hooi Linn, Liang, Jiaqi, Ho, Peiying, Cui, Liang, Chan, Cheryl Siew Choo, Begley, Thomas, Kline, Kimberly Ann, Dedon, Peter
Published 2023

Backbone resonance assignment for the N-terminal region of bacterial tRNA-(N1G37) methyltransferase

by Yan, Li, Zhong, Wenhe, Koay, Ann Zhufang, Ng, Hui Qi, Koh‑Stenta, Xiaoying, Nah, Qianhui, Lim, Siau Hoi, Larsson, Andreas, Lescar, Julien, Hill, Jeffrey, Dedon, Peter C., Kang, CongBao
Published 2021

Functional characterization of the m⁶A-dependent translational modulator PfYTH.2 in the human malaria parasite

by Sinha, Ameya, Baumgarten, Sebastian, Distiller, Amy, McHugh, Emma, Chen, Patty, Singh, Meetali, Bryant, Jessica M., Liang, Jiaqi, Cecere, Germano, Dedon, Peter C., Preiser, Peter Rainer, Ralph, Stuart A., Scherf, Artur
Published 2022

Allosteric pyruvate kinase-based “logic gate” synergistically senses energy and sugar levels in Mycobacterium tuberculosis

by Zhong, Wenhe, Cui, Liang, Goh, Boon Chong, Cai, Qixu, Ho, Peiying, Chionh, Yok Hian, Yuan, Meng, Sahili, Abbas El, Fothergill-Gilmore, Linda A., Walkinshaw, Malcolm D., Lescar, Julien, Dedon, Peter Christian
Published 2018

Antimicrobial resistance in the Asia Pacific region : a meeting report

by Yam, Esabelle Lo Yan, Hsu, Li Yang, Yap, Eric Peng-Huat, Yeo, Tsin Wen, Lee, Vernon, Schlundt, Joergen, Lwin, May Oo, Limmathurotsakul, Direk, Jit, Mark, Dedon, Peter, Turner, Paul, Wilder-Smith, Annelies
Published 2021

Pyruvate kinase regulates the pentose-phosphate pathway in response to hypoxia in mycobacterium tuberculosis

by Zhong, Wenhe, Guo, Jingjing, Cui, Liang, Chionh, Yok Hian, Li, Kuohan, El Sahili, Abbas, Cai, Qixu, Yuan, Meng, Michels, Paul A. M., Fothergill-Gilmore, Linda A., Walkinshaw, Malcolm D., Mu, Yuguang, Lescar, Julien, Dedon, Peter C.
Published 2021

Rifaximin potentiates clarithromycin against Mycobacterium abscessus in vitro and in zebrafish

by Goh, Boon Chong, Larsson, Simon, Dam, Linh Chi, Ling, Sharon Yan Han, Chua, Patrina Wei Lin, Abirami, R., Singh, Samsher, Ong, Ernest Jun Long, Teo, Jeanette W. P., Ho, Peiying, Ingham, Philip William, Pethe, Kevin, Dedon, Peter C.
Published 2024

Quantifying the RNA cap epitranscriptome reveals novel caps in cellular and viral RNA

by Wang, Jin, Chew, Alvin Bing Liang, Lai, Yong, Dong, Hongping, Xu, Luang, Balamkundu, Seetharamsingh, Cai, Maggie Weiling, Cui, Liang, Liu, Chuan Fa, Fu, Xin-Yuan, Lin, Zhenguo, Shi, Pei-Yong, Lu, Timothy K., Luo, Dahai, Jaffrey, Samie R., Dedon, Peter C.
Published 2020

Thienopyrimidinone derivatives that inhibit bacterial tRNA (guanine37-N1)-methyltransferase (TrmD) by restructuring the active site with a tyrosine-flipping mechanism

by Zhong, Wenhe, Pasunooti, Kalyan Kumar, Balamkundu, Seetharamsing, Wong, Yee Hwa, Nah, Qianhui, Gadi, Vinod, Gnanakalai, Shanmugavel, Chionh, Yok Hian, McBee, Megan E., Gopal, Pooja, Lim, Siau Hoi, Olivier, Nelson, Buurman, Ed T., Dick, Thomas, Liu, Chuan Fa, Lescar, Julien, Dedon, Peter C.
Published 2021

Targeting the bacterial epitranscriptome for antibiotic development : discovery of novel tRNA-(N1G37) methyltransferase (TrmD) inhibitors

by Zhong, Wenhe, Koay, Ann, Ngo, Anna, Li, Yan, Nah, Qianhui, Wong, Yee Hwa, Chionh, Yok Hian, Ng, Hui Qi, Koh-Stenta, Xiaoying, Poulsen, Anders, Foo, Klement, McBee, Megan, Choong, Meng Ling, El Sahili, Abbas, Kang, Congbao, Matter, Alex, Lescar, Julien, Hill, Jeffrey, Dedon, Peter
Published 2021

A multidimensional platform for the purification of non-coding RNA species

by Ho, Chia-Hua, Pruksakorn, Dumnoensun, Babu, I. Ramesh, Ng, Chee Sheng, Hia, Fabian, Chionh, Yok Hian, McBee, Megan E., Su, Dan, Pang, Yan Ling Joy, Gu, Chen, Dong, Hongping, Prestwich, Erin G., Shi, Pei-Yong, Preiser, Peter Rainer, Alonso, Sylvie, Dedon, Peter C.
Published 2013

Four additional natural 7-deazaguanine derivatives in phages and how to make them

by Cui, Liang, Balamkundu, Seetharamsing, Liu, Chuan-Fa, Ye, Hong, Hourihan, Jacob, Rausch, Astrid, Hauß, Christopher, Nilsson, Emelie, Hoetzinger, Matthias, Holmfeldt, Karin, Zhang, Weijia, Martinez-Alvarez, Laura, Peng, Xu, Tremblay, Denise, Moinau, Sylvain, Solonenko, Natalie, Sullivan, Matthew B., Lee, Yan-Jiun, Mulholland, Andrew, Weigele, Peter R., de Crécy-Lagard, Valérie, Dedon, Peter C., Hutinet, Geoffrey
Published 2024