Thiazolidin-5-imine formation as a catalyst-free bioorthogonal reaction for protein and live cell labeling

Thiazolidin-5-imine formation as a catalyst-free bioorthogonal reaction for protein and live cell labeling

A previously undescribed reaction involving the formation of a thiazolidin-5-imine linkage was developed for bioconjugation. Being highly specific and operating in aqueous media, this simple condensation reaction is used to chemoselectively label peptides, proteins, and living cells under physiologi...

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Bibliographic Details
Main Authors: Bi, Xiaobao, Yin, Juan, Rao, Chang, Balamkundu, Seetharamsing, Banerjee, Biplab, Zhang, Dingpeng, Zhang, Dawei, Dedon, Peter C., Liu, Chuan-Fa
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2021
Subjects:
Science::Biological sciences
Chemical Structure
Fluorescence Imaging
Online Access:https://hdl.handle.net/10356/150739
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/150739

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