Thiazolidin-5-imine formation as a catalyst-free bioorthogonal reaction for protein and live cell labeling
A previously undescribed reaction involving the formation of a thiazolidin-5-imine linkage was developed for bioconjugation. Being highly specific and operating in aqueous media, this simple condensation reaction is used to chemoselectively label peptides, proteins, and living cells under physiologi...
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Main Authors: | Bi, Xiaobao, Yin, Juan, Rao, Chang, Balamkundu, Seetharamsing, Banerjee, Biplab, Zhang, Dingpeng, Zhang, Dawei, Dedon, Peter C., Liu, Chuan-Fa |
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Other Authors: | School of Biological Sciences |
Format: | Article |
Language: | English |
Published: |
2021
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/150739 |
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Institution: | Nanyang Technological University |
Language: | English |
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