Detection of damaged DNA by capillary electrophoresis with laser induced fluorescence using labelled abasic sites

Abasic sites in DNA can be generated by excision of damage bases. Abasic sites if left unrepaired are known to be mutagenic or lethal. These sites occur spontaneously and their rate of formation is significantly increased in the presence of DNA damage agents. A quant. measure for this lesion would t...

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Bibliographic Details
Main Authors: Fundador, Erwin Oliver V., Rusling, James
Format: text
Published: Animo Repository 2005
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Online Access:https://animorepository.dlsu.edu.ph/faculty_research/5520
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Institution: De La Salle University