Detection of labeled abasic sites in damaged DNA by capillary electrophoresis with laser-induced fluorescence

Removal of nucleobases from the DNA backbone leads to the formation of abasic sites. The rate of abasic site formation is significantly increased for chemically damaged nucleobases. Thus, abasic sites serve as general biomarkers for the quantification of DNA damage. Herein, we show that capillary el...

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Bibliographic Details
Main Authors: Fundador, Erwin Oliver V., Rusling, James
Format: text
Published: Animo Repository 2007
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Online Access:https://animorepository.dlsu.edu.ph/faculty_research/5577
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Institution: De La Salle University