NS5 from dengue virus serotype 2 can adopt a conformation analogous to that of its Zika virus and Japanese encephalitis virus homologues

NS5 from dengue virus serotype 2 can adopt a conformation analogous to that of its Zika virus and Japanese encephalitis virus homologues

Flavivirus nonstructural protein 5 (NS5) contains an N-terminal methyltransferase (MTase) domain and a C-terminal polymerase (RNA-dependent RNA polymerase [RdRp]) domain fused through a 9-amino-acid linker. While the individual NS5 domains are structurally conserved, in the full-length protein, thei...

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Bibliographic Details
Main Authors: El Sahili, Abbas, Soh, Sherryl Tingjin, Schiltz, Jonas, Gharbi-Ayachi, Aïcha, Seh, Cheah Chen, Shi, Pei-Yong, Lim, Siew Pheng, Lescar, Julien
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2020
Subjects:
Science::Biological sciences
Flaviviruses
Dengue Virus
Online Access:https://hdl.handle.net/10356/142215
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/142215

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