Non-nucleoside inhibitors of Zika virus RNA-dependent RNA polymerase

• المؤلفون الرئيسيون: Gharbi-Ayachi, Aïcha, Santhanakrishnan, Sridhar, Wong, Yee Hwa, Chan, Kitti Wing Ki, Tan, Siok Thing, Bates, Roderick Wayland, Vasudevan, Subhash G., El Sahili, Abbas, Lescar, Julien
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: مقال
• اللغة: English
• منشور في: 2020
• الموضوعات: Science::Biological sciences; Nonstructural Protein 5; Polymerase Inhibitors
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/145332
• المؤسسة: Nanyang Technological University

Zika virus (ZIKV) remains a potentially significant public health concern because it can cause teratogenic effects, such as microcephaly in newborns and neurological disease, like Guillain-Barré syndrome. Together with efforts to develop a vaccine, the discovery of antiviral molecules is important t...