Functional Evolution in Orthologous Cell-encoded RNA-dependent RNA Polymerases

by Qian, Xinlei, Hamid, Fursham M., El Sahili, Abbas, Darwis, Dina Amallia, Wong, Yee Hwa, Bhushan, Shashi, Makeyev, Eugene V., Lescar, Julien
Published 2016

Switching Heavy Chain Constant Domains Denatures the Paratope 3D Architecture of Influenza Monoclonal Antibodies

by Malisheni, Moffat MM, Chong, Cheng-Shoong, Murali, Tanusya MM, Purushotorman, Kiren, Qian, Xinlei, Laiman, Alfred, Tan, Yee-Joo, MacAry, Paul AA
Published 2023

SHEAR saliva collection device augments sample properties for improved analytical performance

by Song, Shang Wei, Gupta, Rashi, Jothilingam, Niharika, Qian, Xinlei, Gu, Yue, Lee, V Vien, Sapanel, Yoann, Allen, David Michael, Wong, John Eu Li, MacAry, Paul, Ho, Dean, Blasiak, Agata
Published 2023

SARS-CoV-2 S protein:ACE2 interaction reveals novel allosteric targets

by Raghuvamsi, Palur V, Tulsian, Nikhil K, Samsudin, Firdaus, Qian, Xinlei, Purushotorman, Kiren, Yue, Gu, Kozma, Mary M, Hwa, Wong Y, Lescar, Julien, Bond, Peter J, MacAry, Paul A, Anand, Ganesh S
Published 2021

Defining neutralization and allostery by antibodies against COVID-19 variants

by Tulsian, Nikhil Kumar, Palur, Raghuvamsi Venkata, Qian, Xinlei, Gu, Yue, Shunmuganathan, Bhuvaneshwari, Samsudin, Firdaus, Wong, Yee Hwa, Lin, Jianqing, Purushotorman, Kiren, Kozma, Mary McQueen, Wang, Bei, Lescar, Julien, Wang, Cheng-, Gupta, Ravindra Kumar, Bond, Peter John, MacAry, Paul Anthony
Published 2024

Relative deficiency in interferon-γ-secreting CD4+T cells is strongly associated with poorer COVID-19 vaccination responses in older adults

by Ho, Vanda WT, Boon, Low Heng, Cui, Jianzhou, Juequn, Zhou, Shunmuganathan, Bhuvaneshwari, Gupta, Rashi, Tan, Nikki YJ, Qian, Xinlei, Purushotorman, Kiren, Fong, Siew-Wai, Renia, Laurent, Ng, Lisa FP, Angeli, Veronique, Chen, Jinmiao, Kennedy, Brian K, Ong, Catherine WM, Macary, Paul A
Published 2024

Defining neutralization and allostery by antibodies against COVID-19 variants

by Tulsian, Nikhil Kumar, Palur, Raghuvamsi Venkata, Qian, Xinlei, Gu, Yue, Bhuvaneshwari D/O Shunmuganathan, Samsudin, Firdaus, Wong, Yee Hwa, Lin, Jianqing, Purushotorman, Kiren, Kozma, Mary McQueen, Wang, Bei, Lescar, Julien, Wang, Cheng-I, Gupta, Ravindra Kumar, Bond, Peter John, MacAry, Paul Anthony
Published 2024

Relative deficiency in interferon-γ-secreting CD4+ T cells is strongly associated with poorer COVID-19 vaccination responses in older adults

by Ho, Vanda W. T., Boon, Low Heng, Cui, Jianzhou, Juequn, Zhou, Shunmuganathan, Bhuvaneshwari, Gupta, Rashi, Tan, Nikki Y. J., Qian, Xinlei, Purushotorman, Kiren, Fong, Siew-Wai, Renia, Laurent, Ng, Lisa F. P., Angeli, Veronique, Chen, Jinmiao, Kennedy, Brian K., Ong, Catherine W. M., Macary, Paul A.
Published 2024

An anti-LpqH human monoclonal antibody from an asymptomatic individual mediates protection against <i>Mycobacterium tuberculosis</i>

by Krishnananthasivam, Shivankari, Li, Hao, Bouzeyen, Rania, Shunmuganathan, Bhuvaneshwari, Purushotorman, Kiren, Liao, Xinlei, Du, Fengjiao, Friis, Claudia Guldager Kring, Crawshay-Williams, Felicity, Boon, Low Heng, Qian, Xinlei, Chan, Conrad En Zuo, Sobota, Radoslaw, Kozma, Mary, Jo, Valeria Barcelli, Wang, Guirong, Huang, Hairong, Floto, Andreas, Bifani, Pablo, Javid, Babak, Macary, Paul A
Published 2024

Author Correction: An anti-LpqH human monoclonal antibody from an asymptomatic individual mediates protection against <i>Mycobacterium tuberculosis </i>(vol 8, 136, 2023)

by Krishnananthasivam, Shivankari, Li, Hao, Bouzeyen, Rania, Shunmuganathan, Bhuvaneshwari, Purushotorman, Kiren, Liao, Xinlei, Du, Fengjiao, Friis, Claudia Guldager Kring, Crawshay-Williams, Felicity, Boon, Low Heng, Qian, Xinlei, Chan, Conrad En Zuo, Sobota, Radoslaw, Kozma, Mary, Jo, Valeria Barcelli, Wang, Guirong, Huang, Hairong, Floto, Andreas, Bifani, Pablo, Javid, Babak, Macary, Paul A
Published 2024

Employment of a high throughput functional assay to define the critical factors that influence vaccine induced cross-variant neutralizing antibodies for SARS-CoV-2

by Gu, Yue, Shunmuganathan, Bhuvaneshwari, Qian, Xinlei, Gupta, Rashi, Tan, Rebecca S. W., Kozma, Mary, Purushotorman, Kiren, Murali, Tanusya M., Tan, Nikki Y. J., Preiser, Peter Rainer, Lescar, Julien, Nasir, Haziq, Somani, Jyoti, Tambyah, Paul A., Smith, Kenneth G. C., Renia, Laurent, Ng, Lisa F. P., Lye, David C., Young, Barnaby E., MacAry, Paul A.
Published 2024

A rapid simple point-of-care assay for the detection of SARS-CoV-2 neutralizing antibodies

by Kongsuphol, Patthara, Jia, Huan, Cheng, Hoi Lok, Gu, Yue, Shunmuganathan, Bhuvaneshwari, Chen, Ming Wei, Lim, Sing Mei, Ng, Say Yong, Tambyah, Paul Ananth, Nasir, Haziq, Gao, Xiaohong, Tay, Dousabel, Kim, Seunghyeon, Gupta, Rashi, Qian, Xinlei, Kozma, Mary M, Purushotorman, Kiren, McBee, Megan E, MacAry, Paul A, Sikes, Hadley D, Preiser, Peter R
Published 2023

Efficient recall of SARS-CoV-2 variant-reactive B cells and T responses in the elderly upon heterologous mRNA vaccines as boosters

by Rouers, Angeline, Wong, Nathan, Goh, Yun Shan, Torres-Ruesta, Anthony, Tay, Matthew Zirui, Chang, Zi Wei, Fong, Siew-Wai, Neo, Vanessa, Kam, Isaac Kai Jie, Yeo, Nicholas Kim-Wah, Huang, Yuling, Loh, Chiew Yee, Hor, Pei Xiang, Wong, Joel Xu En, Tan, Yong Jie, Macary, Paul A., Qian, Xinlei, Bei, Wang, Ngoh, Eve Zi Xian, Salleh, Siti Nazihah Mohd, Wang, Cheng-I, Poh, Xuan Ying, Rao, Suma, Chia, Po Ying, Ong, Sean W. X., Lee, Tau Hong, Lin, Ray J. H., Lim, Clarissa, Teo, Jefanie, Ren, Ee Chee, Lye, David C., Young, Barnaby Edward, Ng, Lisa F. P., Renia, Laurent
Published 2023

Efficient recall of SARS-CoV-2 variant-reactive B cells and T responses in the elderly upon heterologous mRNA vaccines as boosters

by Rouers, Angeline, Wong, Nathan, Goh, Yun Shan, Torres-Ruesta, Anthony, Tay, Matthew Zirui, Chang, Zi Wei, Fong, Siew-Wai, Neo, Vanessa, Kam, Isaac Kai Jie, Yeo, Nicholas Kim-Wah, Huang, Yuling, Loh, Chiew Yee, Hor, Pei Xiang, Wong, Joel Xu En, Tan, Yong Jie, Macary, Paul A, Qian, Xinlei, Wang Bei, Ngoh, Eve Zi Xian, Salleh, Siti Nazihah Mohd, Wang, Cheng-, Poh, Xuan Ying, Rao, Suma, Chia, Po Ying, Ong, Sean WX, Lee, Tau Hong, Lin, Ray JH, Lim, Clarissa, Teo, Jefanie, Ren, Ee Chee, Lye, David Chien, Young, Barnaby E, Ng, Lisa FP, Renia, Laurent
Published 2023

Employment of a high throughput functional assay to define the critical factors that influence vaccine induced cross-variant neutralizing antibodies for SARS-CoV-2

by Gu, Yue, Shunmuganathan, Bhuvaneshwari, Qian, Xinlei, Gupta, Rashi, Tan, Rebecca SW, Kozma, Mary, Purushotorman, Kiren, Murali, Tanusya M, Tan, Nikki YJ, Preiser, Peter R, Lescar, Julien, Nasir, Haziq, Somani, Jyoti, Tambyah, Paul A, Fong, Siew-Wai, Amrun, Siti Naqiah, Goh, Yun-Shan, Tay, Matthew Zi-Rui, Rouers, Angeline, Chang, Zi Wei, Yeo, Nicholas Kim-Wah, Chan, Yi-Hao, Hor, Pei Xian, Loh, Chiew Yee, Yang, Yuling, Ruesta, Anthony Torres, Neo, Vanessa, Chen, Wendy Yehui, Goh, Estelle Yi-Wei, Ong, Alice Soh-Meoy, Chua, Adeline Chiew Yen, Nguee, Samantha, Tang, Yong Jie, Tang, Weiyi, Wong, Joel Xu En, Smith, Kenneth GC, Renia, Laurent, Ng, Lisa FP, Lye, David C, Young, Barnaby E, Macary, Paul A
Published 2024