Mimicking immune signatures of flavivirus infection with targeted adjuvants improves dengue subunit vaccine immunogenicity

Mimicking immune signatures of flavivirus infection with targeted adjuvants improves dengue subunit vaccine immunogenicity

Neutralizing antibodies (nAbs) are a critical component for protection against dengue virus (DENV) infection, but little is known about the immune mechanisms governing their induction and whether such mechanisms can be harnessed for vaccine development. In this study, we profiled the early immune re...

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Bibliographic Details
Main Authors: Bidet, Katell, Ho, Victor, Chu, Collins Wenhan, Ahmad Nazri Mohamed Naim, Thazin, Khaing, Chan, Kuan Rong, Low, Jenny G. H., Choy, Milly M., Wong, Lan Hiong, de Sessions, Paola Florez, Lee, Yie Hou, Hibberd, Martin L., Ooi, Eng Eong, Fink, Katja, Chen, Jianzhu
Other Authors: School of Biological Sciences
Format: Article
Language:English
Published: 2020
Subjects:
Science::Biological sciences
Flavivirus Infection
Vaccine Immunogenicity
Online Access:https://hdl.handle.net/10356/142456
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Institution: Nanyang Technological University
Language: English

Internet

https://hdl.handle.net/10356/142456

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