Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections

• Main Authors: Goh, Yun Shan, Fong, Siew-Wai, Hor, Pei Xiang, Siti Naqiah Amrun, Lee, Cheryl Yi-Pin, Young, Barnaby Edward, Chia, Po Ying, Tambyah, Paul A., Kalimuddin, Shirin, Pada, Surinder, Tan, Seow-Yen, Sun, Louisa Jin, Chen, Mark I-Cheng, Leo, Yee-Sin, Lye, David C., Ng, Lisa F. P., Renia, Laurent
• Format: Article
• Language: English
• Published: 2023
• Subjects: Science::Medicine; Antibodies; COVID-19
• Online Access: https://hdl.handle.net/10356/170781
• Institution: Nanyang Technological University

COVID-19 has a wide disease spectrum ranging from asymptomatic to severe. While humoral immune responses are critical in preventing infection, the immune mechanisms leading to severe disease, and the identification of biomarkers of disease progression and/or resolution of the infection remains to be...