Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections
COVID-19 has a wide disease spectrum ranging from asymptomatic to severe. While humoral immune responses are critical in preventing infection, the immune mechanisms leading to severe disease, and the identification of biomarkers of disease progression and/or resolution of the infection remains to be...
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sg-ntu-dr.10356-1707812023-10-15T15:38:47Z Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections Goh, Yun Shan Fong, Siew-Wai Hor, Pei Xiang Siti Naqiah Amrun Lee, Cheryl Yi-Pin Young, Barnaby Edward Chia, Po Ying Tambyah, Paul A. Kalimuddin, Shirin Pada, Surinder Tan, Seow-Yen Sun, Louisa Jin Chen, Mark I-Cheng Leo, Yee-Sin Lye, David C. Ng, Lisa F. P. Renia, Laurent Science::Medicine Antibodies COVID-19 COVID-19 has a wide disease spectrum ranging from asymptomatic to severe. While humoral immune responses are critical in preventing infection, the immune mechanisms leading to severe disease, and the identification of biomarkers of disease progression and/or resolution of the infection remains to be determined. Agency for Science, Technology and Research (A*STAR) Published version This research was supported by Biomedical Research Council (BMRC), the A*ccelerate GAP-funded project (ACCL/19-GAP064-R20H-H) from Agency of Science, Technology and Research (A*STAR), National Medical Research Council (NMRC) COVID-19 Research fund (COVID19RF-001, COVID-19RF-007, and COVID-19RF-60), and A*STAR COVID-19 Research funding (H/20/04/g1/006). 2023-10-09T05:03:20Z 2023-10-09T05:03:20Z 2022 Journal Article Goh, Y. S., Fong, S., Hor, P. X., Siti Naqiah Amrun, Lee, C. Y., Young, B. E., Chia, P. Y., Tambyah, P. A., Kalimuddin, S., Pada, S., Tan, S., Sun, L. J., Chen, M. I., Leo, Y., Lye, D. C., Ng, L. F. P. & Renia, L. (2022). Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections. Frontiers in Microbiology, 13, 1043049-. https://dx.doi.org/10.3389/fmicb.2022.1043049 1664-302X https://hdl.handle.net/10356/170781 10.3389/fmicb.2022.1043049 36483199 2-s2.0-85143356937 13 1043049 en COVID-19RF-007 COVID-19RF-60 COVID19RF-001 H/20/04/g1/006 Frontiers in Microbiology © 2022 Goh, Fong, Hor, Amrun, Lee,Young, Chia, Tambyah, Kalimuddin, Pada,Tan, Sun, Chen, Leo, Lye, Ng and Renia.This is an open-access article distributed under the terms of creative commons license application/pdf |
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Science::Medicine Antibodies COVID-19 Goh, Yun Shan Fong, Siew-Wai Hor, Pei Xiang Siti Naqiah Amrun Lee, Cheryl Yi-Pin Young, Barnaby Edward Chia, Po Ying Tambyah, Paul A. Kalimuddin, Shirin Pada, Surinder Tan, Seow-Yen Sun, Louisa Jin Chen, Mark I-Cheng Leo, Yee-Sin Lye, David C. Ng, Lisa F. P. Renia, Laurent Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections |
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COVID-19 has a wide disease spectrum ranging from asymptomatic to severe. While humoral immune responses are critical in preventing infection, the immune mechanisms leading to severe disease, and the identification of biomarkers of disease progression and/or resolution of the infection remains to be determined. |
format |
Article |
author |
Goh, Yun Shan Fong, Siew-Wai Hor, Pei Xiang Siti Naqiah Amrun Lee, Cheryl Yi-Pin Young, Barnaby Edward Chia, Po Ying Tambyah, Paul A. Kalimuddin, Shirin Pada, Surinder Tan, Seow-Yen Sun, Louisa Jin Chen, Mark I-Cheng Leo, Yee-Sin Lye, David C. Ng, Lisa F. P. Renia, Laurent |
author_facet |
Goh, Yun Shan Fong, Siew-Wai Hor, Pei Xiang Siti Naqiah Amrun Lee, Cheryl Yi-Pin Young, Barnaby Edward Chia, Po Ying Tambyah, Paul A. Kalimuddin, Shirin Pada, Surinder Tan, Seow-Yen Sun, Louisa Jin Chen, Mark I-Cheng Leo, Yee-Sin Lye, David C. Ng, Lisa F. P. Renia, Laurent |
author_sort |
Goh, Yun Shan |
title |
Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections |
title_short |
Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections |
title_full |
Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections |
title_fullStr |
Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections |
title_full_unstemmed |
Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections |
title_sort |
conserved longitudinal alterations of anti-s-protein igg subclasses in disease progression in initial ancestral wuhan and vaccine breakthrough delta infections |
publishDate |
2023 |
url |
https://hdl.handle.net/10356/170781 |
_version_ |
1781793890939961344 |