Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections

COVID-19 has a wide disease spectrum ranging from asymptomatic to severe. While humoral immune responses are critical in preventing infection, the immune mechanisms leading to severe disease, and the identification of biomarkers of disease progression and/or resolution of the infection remains to be...

Full description

Saved in:
Bibliographic Details
Main Authors: Goh, Yun Shan, Fong, Siew-Wai, Hor, Pei Xiang, Siti Naqiah Amrun, Lee, Cheryl Yi-Pin, Young, Barnaby Edward, Chia, Po Ying, Tambyah, Paul A., Kalimuddin, Shirin, Pada, Surinder, Tan, Seow-Yen, Sun, Louisa Jin, Chen, Mark I-Cheng, Leo, Yee-Sin, Lye, David C., Ng, Lisa F. P., Renia, Laurent
Format: Article
Language:English
Published: 2023
Subjects:
Online Access:https://hdl.handle.net/10356/170781
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Nanyang Technological University
Language: English
id sg-ntu-dr.10356-170781
record_format dspace
spelling sg-ntu-dr.10356-1707812023-10-15T15:38:47Z Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections Goh, Yun Shan Fong, Siew-Wai Hor, Pei Xiang Siti Naqiah Amrun Lee, Cheryl Yi-Pin Young, Barnaby Edward Chia, Po Ying Tambyah, Paul A. Kalimuddin, Shirin Pada, Surinder Tan, Seow-Yen Sun, Louisa Jin Chen, Mark I-Cheng Leo, Yee-Sin Lye, David C. Ng, Lisa F. P. Renia, Laurent Science::Medicine Antibodies COVID-19 COVID-19 has a wide disease spectrum ranging from asymptomatic to severe. While humoral immune responses are critical in preventing infection, the immune mechanisms leading to severe disease, and the identification of biomarkers of disease progression and/or resolution of the infection remains to be determined. Agency for Science, Technology and Research (A*STAR) Published version This research was supported by Biomedical Research Council (BMRC), the A*ccelerate GAP-funded project (ACCL/19-GAP064-R20H-H) from Agency of Science, Technology and Research (A*STAR), National Medical Research Council (NMRC) COVID-19 Research fund (COVID19RF-001, COVID-19RF-007, and COVID-19RF-60), and A*STAR COVID-19 Research funding (H/20/04/g1/006). 2023-10-09T05:03:20Z 2023-10-09T05:03:20Z 2022 Journal Article Goh, Y. S., Fong, S., Hor, P. X., Siti Naqiah Amrun, Lee, C. Y., Young, B. E., Chia, P. Y., Tambyah, P. A., Kalimuddin, S., Pada, S., Tan, S., Sun, L. J., Chen, M. I., Leo, Y., Lye, D. C., Ng, L. F. P. & Renia, L. (2022). Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections. Frontiers in Microbiology, 13, 1043049-. https://dx.doi.org/10.3389/fmicb.2022.1043049 1664-302X https://hdl.handle.net/10356/170781 10.3389/fmicb.2022.1043049 36483199 2-s2.0-85143356937 13 1043049 en COVID-19RF-007 COVID-19RF-60 COVID19RF-001 H/20/04/g1/006 Frontiers in Microbiology © 2022 Goh, Fong, Hor, Amrun, Lee,Young, Chia, Tambyah, Kalimuddin, Pada,Tan, Sun, Chen, Leo, Lye, Ng and Renia.This is an open-access article distributed under the terms of creative commons license application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic Science::Medicine
Antibodies
COVID-19
spellingShingle Science::Medicine
Antibodies
COVID-19
Goh, Yun Shan
Fong, Siew-Wai
Hor, Pei Xiang
Siti Naqiah Amrun
Lee, Cheryl Yi-Pin
Young, Barnaby Edward
Chia, Po Ying
Tambyah, Paul A.
Kalimuddin, Shirin
Pada, Surinder
Tan, Seow-Yen
Sun, Louisa Jin
Chen, Mark I-Cheng
Leo, Yee-Sin
Lye, David C.
Ng, Lisa F. P.
Renia, Laurent
Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections
description COVID-19 has a wide disease spectrum ranging from asymptomatic to severe. While humoral immune responses are critical in preventing infection, the immune mechanisms leading to severe disease, and the identification of biomarkers of disease progression and/or resolution of the infection remains to be determined.
format Article
author Goh, Yun Shan
Fong, Siew-Wai
Hor, Pei Xiang
Siti Naqiah Amrun
Lee, Cheryl Yi-Pin
Young, Barnaby Edward
Chia, Po Ying
Tambyah, Paul A.
Kalimuddin, Shirin
Pada, Surinder
Tan, Seow-Yen
Sun, Louisa Jin
Chen, Mark I-Cheng
Leo, Yee-Sin
Lye, David C.
Ng, Lisa F. P.
Renia, Laurent
author_facet Goh, Yun Shan
Fong, Siew-Wai
Hor, Pei Xiang
Siti Naqiah Amrun
Lee, Cheryl Yi-Pin
Young, Barnaby Edward
Chia, Po Ying
Tambyah, Paul A.
Kalimuddin, Shirin
Pada, Surinder
Tan, Seow-Yen
Sun, Louisa Jin
Chen, Mark I-Cheng
Leo, Yee-Sin
Lye, David C.
Ng, Lisa F. P.
Renia, Laurent
author_sort Goh, Yun Shan
title Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections
title_short Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections
title_full Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections
title_fullStr Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections
title_full_unstemmed Conserved longitudinal alterations of anti-S-protein IgG subclasses in disease progression in initial ancestral Wuhan and vaccine breakthrough Delta infections
title_sort conserved longitudinal alterations of anti-s-protein igg subclasses in disease progression in initial ancestral wuhan and vaccine breakthrough delta infections
publishDate 2023
url https://hdl.handle.net/10356/170781
_version_ 1781793890939961344