EFFECTS OF SPECIFIC HOST FACTORS AND MICRORNAS DURING INFECTIVE AND REGENERATIVE PHASES OF INFLUENZA PNEUMONIA

by TAN KAI SEN
Published 2018

Impact of Respiratory Virus Infections in Exacerbation of Acute and Chronic Rhinosinusitis

by Tan, Kai Sen, Yan, Yan, Ong, Hsiao Hui, Chow, Vincent TK, Shi, Li, Wang, De-Yun
Published 2022

Tetraspanins: Host Factors in Viral Infections

by New, ChihSheng, Lee, Zhao-Yong, Tan, Kai Sen, Wong, Amanda Huee-Ping, Wang, De Yun, Tran, Thai
Published 2022

FGF2, an Immunomodulatory Factor in Asthma and Chronic Obstructive Pulmonary Disease (COPD).

by Tan, Yuanyang, Qiao, Yongkang, Chen, Zhuanggui, Liu, Jing, Guo, Yanrong, Tran, Thai, Tan, Kai Sen, Wang, De-Yun, Yan, Yan
Published 2020

Comparative transcriptomic and metagenomic analyses of influenza virus-infected nasal epithelial cells from multiple individuals reveal specific nasal-initiated signatures

by Tan, Kai Sen, Yan, Yan, Koh, Wai Ling Hiromi, Li, Liang, Choi, Hyungwon, Tran, Thai, Sugrue, Richard, Wang, De Yun, Chow, Vincent T.
Published 2018

Micro-RNAs in regenerating lungs: an integrative systems biology analysis of murine influenza pneumonia

by Tan Kai Sen, Choi Hyung Won, Jiang Xiaoou, Yin Lu, SEET JU EE, Volker Patzel, Engelward, Bevin P., CHOW TAK KWONG,VINCENT
Published 2018

A Comparison of retrieved Respiratory Viral Load emitted by infected SARS-CoV-2 patients

by Tham, Kwok Wai, Coleman, Kristen, Tay, Douglas, Ong, Ong, Tan, Kai Sen, Milton, Don, Koh, ming hui, Chow, TK, Chen, Mark, Tambyah, Paul
Published 2022

Early pathogenesis profiles across SARS-CoV-2 variants in K18-hACE2 mice revealed differential triggers of lung damages

by Aw, Zhen Qin, Mok, Chee Keng, Wong, Yi Hao, Chen, Huixin, Mak, Tze Minn, Lin, Raymond T. P., Lye, David C., Tan, Kai Sen, Chu, Justin Jang Hann
Published 2023

Early pathogenesis profiles across SARS-CoV-2 variants in K18-hACE2 mice revealed differential triggers of lung damages

by Aw, Zhen Qin, Mok, Chee Keng, Wong, Yi Hao, Chen, Huixin, Mak, Tze Minn, Lin, Raymond TP, Lye, David Chien, Tan, Kai Sen, Chu, Justin Jang Hann
Published 2022

Induction of IL-25 Expression in Human Nasal Polyp Epithelium by Influenza Virus Infection is Abated by Interferon-Alpha Pretreatment

by Hong, Haiyu, Tan, Kai Sen, Yan, Yan, Chen, Fenghong, Ong, Hsiao Hui, Oo, Yukei, Liu, Jing, Ong, Yew Kwang, Thong, Mark, Sugrue, Richard, Chow, Vincent T, Wang, De Yun
Published 2022

Transcriptomics of rhinovirus persistence reveals sustained expression of RIG-I and interferon-stimulated genes in nasal epithelial cells in vitro

by Ong, Hsiao Hui, Andiappan, Anand Kumar, Duan, Kaibo, Lum, Josephine, Liu, Jing, Tan, Kai Sen, Howland, Shanshan, Lee, Bernett, Ong, Yew Kwang, Thong, Mark, Chow, Vincent T, Wang, De-Yun
Published 2022

Detection of hospital environmental contamination during SARS-CoV-2 Omicron predominance using a highly sensitive air sampling device

by Tan, Kai Sen, Ang, Alicia Xin Yu, Tay, Douglas Jie Wen, Somani, Jyoti, Ng, Alexander Jet Yue, Peng, Li Lee, Chu, Justin Jang Hann, Tambyah, Paul Anantharajah, Allen, David Michael
Published 2023

Generation of self-replicating airway organoids from the cave nectar bat Eonycteris spelaea as a model system for studying host-pathogen interactions in the bat airway epithelium

by Chan, Louisa L. Y., Gamage, Akshamal M., Tan, Chee Wah, Tan, Kai Sen, Liu, Jing, Tay, Douglas Jie Wen, Foo, Randy Jee Hiang, Rénia, Laurent, Wang, De Yun, Wang, Lin-Fa
Published 2023

Enteroviral 3C protease activates the human NLRP1 inflammasome in airway epithelia.

by Robinson, Kim S, Teo, Daniel Eng Thiam, Tan, Kai Sen, Toh, Gee Ann, Ong, Hsiao Hui, Lim, Chrissie Kaishi, Lay, Kenneth, Au, Bijin Veonice, Lew, Tian Sheng, Chu, Justin Jang Hann, Chow, Vincent Tak Kwong, Wang, De Yun, Zhong, Franklin L, Reversade, Bruno
Published 2020

Viral Load of SARS-CoV-2 in Respiratory Aerosols Emitted by COVID-19 Patients while Breathing, Talking, and Singing

by Coleman, Kristen K, DOUGLAS JIE WEN TAY, Tan Kai Sen, Ong, Sean Wei Xiang, THAN THE SON, MING HUI KOH, Chin, Yi Qing, Nasir, Haziq, Mak, Tze Minn, CHU JANG HANN, Milton, Donald K, CHOW TAK KWONG,VINCENT, PAUL ANANTHARAJAH TAMBYAH, Chen, Mark, THAM KWOK WAI
Published 2021

Human Nasal Epithelial Cells Sustain Persistent SARS-CoV-2 Infection In Vitro, despite Eliciting a Prolonged Antiviral Response

by Gamage, Akshamal M, Tan, Kai Sen, Chan, Wharton OY, Lew, Zhe Zhang Ryan, Liu, Jing, Tan, Chee Wah, Rajagopalan, Deepa, Lin, Quy Xiao Xuan, Tan, Le Min, Venkatesh, Prasanna Nori, Ong, Yew Kwang, Thong, Mark, Lin, Raymond Tzer Pin, Prabhakar, Shyam, Wang, De Yun, Wang, Lin-Fa
Published 2022

Evaluation of In Vitro and In Vivo Antiviral Activities of Vitamin D for SARS-CoV-2 and Variants

by Mok, Chee-Keng, Ng, Yan Ling, Ahidjo, Bintou Ahmadou, Aw, Zhen Qin, Chen, Huixin, Wong, Yi Hao, Lee, Regina Ching Hua, Loe, Marcus Wing Choy, Liu, Jing, Tan, Kai Sen, Kaur, Parveen, Wang, De Yun, Hao, Erwei, Hou, Xiaotao, Tan, Yong Wah, Deng, Jiagang, Chu, Justin Jang Hann
Published 2023

Abnormal Expression of YAP Is Associated With Proliferation, Differentiation, Neutrophil Infiltration, and Adverse Outcome in Patients With Nasal Inverted Papilloma

by Yuan, Tian, Zheng, Rui, Zhou, Xiang-min, Jin, Peng, Huang, Zhi-qun, Zi, Xiao-xue, Wu, Qing-wu, Wang, Wei-hao, Deng, Hui-yi, Kong, Wei-feng, Qiu, Hui-jun, Zhou, Sui-zi, Chen, Qian-min, Tu, Yan-yi, Li, Tao, Liu, Jing, Tan, Kai Sen, Ong, Hsiao Hui, Shi, Li, Chen, Zhuang-gui, Huang, Xue-kun, Yang, Qin-tai, Wang, De-yun
Published 2022

Red Blood Cell-Derived Extracellular Vesicles Display Endogenous Antiviral Effects and Enhance the Efficacy of Antiviral Oligonucleotide Therapy

by Jayasinghe, Migara K, Gao, Chang, Yap, Gracemary, Yeo, Brendon Zhi Jie, Vu, Luyen Tien, Tay, Douglas Jie Wen, Loh, Wen Xiu, Aw, Zhen Qin, Chen, Huixin, Phung, Dai Cao, Hoang, Dong Van, Prajogo, Rebecca Carissa, Hooi, Lissa, Lim, Fang Qing, Pirisinu, Marco, Mok, Chee Keng, Lim, Kah Wai, Tang, Sze Jing, Tan, Kai Sen, Chow, Edward Kai-Hua, Chen, Leilei, Phan, Anh Tuan, Chu, Justin Jang Hann, Le, Minh TN
Published 2024

Neisseria species as pathobionts in bronchiectasis

by Li, Liang, Aogáin, Micheál Mac, Xu, Tengfei, Jaggi, Tavleen Kaur, Chan, Louisa L. Y., Qu, Jing, Wei, Lan, Liao, Shumin, Cheng, Hong Sheng, Keir, Holly R., Dicker, Alison J., Tan, Kai Sen, Yun, Wang, De, Koh, Mariko Siyue, Ong, Thun How, Lim, Albert Yick Hou, Abisheganaden, John A., Low, Teck Boon, Hassan, Tidi Maharani, Long, Xiang, Wark, Peter A. B., Oliver, Brian, Drautz-Moses, Daniela I., Schuster, Stephan Christoph, Tan, Nguan Soon, Fang, Mingliang, Chalmers, James D., Chotirmall, Sanjay Haresh
Published 2023