Early pathogenesis profiles across SARS-CoV-2 variants in K18-hACE2 mice revealed differential triggers of lung damages

by Aw, Zhen Qin, Mok, Chee Keng, Wong, Yi Hao, Chen, Huixin, Mak, Tze Minn, Lin, Raymond T. P., Lye, David C., Tan, Kai Sen, Chu, Justin Jang Hann
Published 2023

Early pathogenesis profiles across SARS-CoV-2 variants in K18-hACE2 mice revealed differential triggers of lung damages

by Aw, Zhen Qin, Mok, Chee Keng, Wong, Yi Hao, Chen, Huixin, Mak, Tze Minn, Lin, Raymond TP, Lye, David Chien, Tan, Kai Sen, Chu, Justin Jang Hann
Published 2022

A Potent and Protective Human Neutralizing Antibody Against SARS-CoV-2 Variants

by Shan, Sisi, Mok, Chee Keng, Zhang, Shuyuan, Lan, Jun, Li, Jizhou, Yang, Ziqing, Wang, Ruoke, Cheng, Lin, Fang, Mengqi, Aw, Zhen Qin, Yu, Jinfang, Zhang, Qi, Shi, Xuanling, Zhang, Tong, Zhang, Zheng, Wang, Jianbin, Wang, Xinquan, Chu, Justin Jang Hann, Zhang, Linqi
Published 2022

Flavivirus genome recoding by codon optimisation confers genetically stable <i>in vivo</i> attenuation in both mice and mosquitoes

by Chin, Wei-Xin, Kong, Hao Yuin, Zhu, Isabelle Xin Yu, Teo, Zi Yun, Faruk, Regina, Lee, Regina Ching Hua, Ho, Si Xian, Aw, Zhen Qin, Yi, Bowen, Hou, Xin Jun, Tan, Antson Kiat Yee, Yogarajah, Thinesshwary, Huber, Roland G, Cai, Yu, Wan, Yue, Chu, Justin Jang Hann
Published 2024

Infection with wild-type SARS-CoV-2 elicits broadly neutralizing and protective antibodies against omicron subvariants

by Ju, Bin, Zhang, Qi, Wang, Ziyi, Aw, Zhen Qin, Chen, Peng, Zhou, Bing, Wang, Ruoke, Ge, Xiangyang, Lv, Qining, Cheng, Lin, Zhang, Rui, Wong, Yi Hao, Chen, Huixin, Wang, Haiyan, Shan, Sisi, Liao, Xuejiao, Shi, Xuanling, Liu, Lei, Chu, Justin Jang Hann, Wang, Xinquan, Zhang, Zheng, Zhang, Linqi
Published 2023

Evaluation of In Vitro and In Vivo Antiviral Activities of Vitamin D for SARS-CoV-2 and Variants

by Mok, Chee-Keng, Ng, Yan Ling, Ahidjo, Bintou Ahmadou, Aw, Zhen Qin, Chen, Huixin, Wong, Yi Hao, Lee, Regina Ching Hua, Loe, Marcus Wing Choy, Liu, Jing, Tan, Kai Sen, Kaur, Parveen, Wang, De Yun, Hao, Erwei, Hou, Xiaotao, Tan, Yong Wah, Deng, Jiagang, Chu, Justin Jang Hann
Published 2023

Broadly neutralizing and protective nanobodies against SARS-CoV-2 Omicron subvariants BA.1, BA.2, and BA.4/5 and diverse sarbecoviruses

by Li, Mingxi, Ren, Yifei, Aw, Zhen Qin, Chen, Bo, Yang, Ziqing, Lei, Yuqing, Cheng, Lin, Liang, Qingtai, Hong, Junxian, Yang, Yiling, Chen, Jing, Wong, Yi Hao, Wei, Jing, Shan, Sisi, Zhang, Senyan, Ge, Jiwan, Wang, Ruoke, Dong, Jay Zengjun, Chen, Yuxing, Shi, Xuanling, Zhang, Qi, Zhang, Zheng, Chu, Justin Jang Hann, Wang, Xinquan, Zhang, Linqi
Published 2023

Red Blood Cell-Derived Extracellular Vesicles Display Endogenous Antiviral Effects and Enhance the Efficacy of Antiviral Oligonucleotide Therapy

by Jayasinghe, Migara K, Gao, Chang, Yap, Gracemary, Yeo, Brendon Zhi Jie, Vu, Luyen Tien, Tay, Douglas Jie Wen, Loh, Wen Xiu, Aw, Zhen Qin, Chen, Huixin, Phung, Dai Cao, Hoang, Dong Van, Prajogo, Rebecca Carissa, Hooi, Lissa, Lim, Fang Qing, Pirisinu, Marco, Mok, Chee Keng, Lim, Kah Wai, Tang, Sze Jing, Tan, Kai Sen, Chow, Edward Kai-Hua, Chen, Leilei, Phan, Anh Tuan, Chu, Justin Jang Hann, Le, Minh TN
Published 2024