Flavivirus genome recoding by codon optimisation confers genetically stable <i>in vivo</i> attenuation in both mice and mosquitoes

• Main Authors: Chin, Wei-Xin, Kong, Hao Yuin, Zhu, Isabelle Xin Yu, Teo, Zi Yun, Faruk, Regina, Lee, Regina Ching Hua, Ho, Si Xian, Aw, Zhen Qin, Yi, Bowen, Hou, Xin Jun, Tan, Antson Kiat Yee, Yogarajah, Thinesshwary, Huber, Roland G, Cai, Yu, Wan, Yue, Chu, Justin Jang Hann
• Other Authors: BIOLOGICAL SCIENCES
• Format: Article
• Language: English
• Published: PUBLIC LIBRARY SCIENCE 2024
• Subjects: Science & Technology; Life Sciences & Biomedicine; Microbiology; Parasitology; Virology; DENGUE VIRUS; RNA REPLICATION; VACCINE VIRUS; ELEMENT; REGION; PAIR; CYCLIZATION; MARKERS; PDK-53
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/246879
• Institution: National University of Singapore

10.1371/journal.ppat.1011753