Polygenic risk scores for complex diseases: where are we now?

Polygenic risk scores (PRS), commonly referred to as genetic or genomic risk scores, aggregate the effects of multiple genetic variants into a single composite estimate of genetic risk. PRS scores are typically used to predict the risk of developing a disease or to explain the phenotypic variation,...

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Bibliographic Details
Main Authors: Loh, Marie, Chambers, John Campbell
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Article
Language:English
Published: 2023
Subjects:
Online Access:https://hdl.handle.net/10356/169414
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Institution: Nanyang Technological University
Language: English